1. Gene
  2. Id1 - inhibitor of DNA binding 1 Gene

Id1 - inhibitor of DNA binding 1 Gene

种属: Rattus norvegicus

同用名: Idb1; ID125A

基因 ID: 25261 | 基因类型: protein coding

关于 Id1

功能概要

Enables several functions, including identical protein binding activity; Proteasome binding activity; and protein C-terminus binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to organonitrogen compound; and nervous system development. Located in centrosome and nucleus. Used to study pulmonary hypertension. Biomarker of cholestasis. Orthologous to human ID1 (inhibitor of DNA binding 1, HLH protein). [provided by Alliance of Genome Resources, Apr 2022]

Id1 基因产物(2)

mRNA Protein Name
NM_012797.2 NP_036929.2 DNA-binding protein inhibitor ID-1
NM_012797.2 NP_036929.2 DNA-binding protein inhibitor ID-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
8106493 RGD
enables proteasome binding IPI
IPI: 通过物理相互作用推断
23831032 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
19167333 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell-abiotic substrate adhesion IEP
IEP: 通过表达模式推断
11600477 RGD
involved in cellular response to dopamine IEP
IEP: 通过表达模式推断
20600660 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
7623812 RGD
involved in cellular response to nerve growth factor stimulus IEP
IEP: 通过表达模式推断
7623812 RGD
involved in cellular response to peptide IEP
IEP: 通过表达模式推断
16706836 RGD
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
16628634 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
19137015 RGD
involved in negative regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
19167333 RGD
involved in negative regulation of endothelial cell differentiation IMP
IMP: 通过突变表型推断
20830586 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23831032 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
7908517 RGD
involved in positive regulation of actin filament bundle assembly IMP
IMP: 通过突变表型推断
16628634 RGD
involved in positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
23335245 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
23335245 RGD
involved in regulation of vasculature development IMP
IMP: 通过突变表型推断
21472453 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
20600660 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
19167333 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

DNA-binding protein inhibitor ID-1

Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation)

Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation)

inhibitor of DNA binding 1, HLH protein

inhibitor of DNA binding 1, dominant negative helix-loop-helix prote

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Id1 NCBI NCBI:3397
Mus musculus Id1 NCBI NCBI:15901
Macaca mulatta Id1 NCBI NCBI:713160