2. Gene
  3. Kif5c - kinesin family member 5C Gene

Kif5c - kinesin family member 5C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Khc; KINN; NKHC; NKHC2

基因 ID: 16574 | 基因类型: protein coding

关于 Kif5c

功能概要

Predicted to enable several functions, including ATP hydrolysis activity; Apolipoprotein receptor binding activity; and plus-end-directed microtubule motor activity. Involved in mRNA transport. Acts upstream of or within motor neuron axon guidance. Located in several cellular components, including axonal growth cone; ciliary rootlet; and neuronal cell body. Is expressed in several structures, including genitourinary system; nervous system; nose; and retina. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 2 and schizophrenia. Orthologous to human KIF5C (Kinesin family member 5C). [provided by Alliance of Genome Resources, Apr 2022]

Kif5c 基因产物(1)

mRNA Protein Name
NM_008449.3 NP_032475.2 kinesin heavy chain isoform 5C
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10602484 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in anterograde dendritic transport of messenger ribonucleoprotein complex IDA
IDA: 通过直接分析推断
34260917 MGI
involved in anterograde dendritic transport of messenger ribonucleoprotein complex IMP
IMP: 通过突变表型推断
34260917 MGI
involved in mRNA transport IMP
IMP: 通过突变表型推断
19608740 MGI
acts upstream of or within motor neuron axon guidance IMP
IMP: 通过突变表型推断
10964943 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axonal growth cone IDA
IDA: 通过直接分析推断
24286867 MGI
located in ciliary rootlet IDA
IDA: 通过直接分析推断
16018997 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
16018997 MGI
located in distal axon IDA
IDA: 通过直接分析推断
24286867 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
16301330 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
24286867 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kinesin heavy chain isoform 5C

kinesin heavy chain member 5C

kinesin heavy chain neuron-specific 2

kinesin-1

Kif5c 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Kif5c P28738 Mapk8ip3 Mus musculus Q9ESN9
Pull Down
21750526
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07291 KIF5C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22598 Kif5c Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29115 Kif5c Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kif5c NCBI NCBI:3800
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