2. Gene
  3. Mapk8ip3 - mitogen-activated protein kinase 8 interacting protein 3 Gene

Mapk8ip3 - mitogen-activated protein kinase 8 interacting protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Jip3; Syd2; JIP-3; JSAP1; JSAP1a; JSAP1b; JSAP1c; JSAP1d; D17Wsu15e; mKIAA1066

基因 ID: 30957 | 基因类型: protein coding

关于 Mapk8ip3

功能概要

Enables MAP-kinase scaffold activity; Kinesin binding activity; and protein kinase binding activity. Involved in several processes, including anterograde axonal protein transport; positive regulation of neuron migration; and regulation of MAPK cascade. Acts upstream of or within several processes, including JNK cascade; lung development; and nervous system development. Located in several cellular components, including Golgi membrane; axolemma; and smooth endoplasmic reticulum. Is expressed in several structures, including brain; extraembryonic component; genitourinary system; lung; and spinal cord. Orthologous to human MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Mapk8ip3 基因产物(7)

mRNA Protein Name
NM_001163447.1 NP_001156919.1 C-Jun-amino-terminal kinase-interacting protein 3 isoform b
NM_001163448.1 NP_001156920.1 C-Jun-amino-terminal kinase-interacting protein 3 isoform c
NM_001163449.1 NP_001156921.1 C-Jun-amino-terminal kinase-interacting protein 3 isoform d
NM_001163450.1 NP_001156922.1 C-Jun-amino-terminal kinase-interacting protein 3 isoform e
NM_001163451.1 NP_001156923.1 C-Jun-amino-terminal kinase-interacting protein 3 isoform f
NM_001163453.1 NP_001156925.1 C-Jun-amino-terminal kinase-interacting protein 3 isoform g
NM_013931.4 NP_038959.2 C-Jun-amino-terminal kinase-interacting protein 3 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables JUN kinase binding IPI
IPI: 通过物理相互作用推断
10523642 MGI
enables MAP-kinase scaffold activity IDA
IDA: 通过直接分析推断
10523642 MGI
enables MAP-kinase scaffold activity IPI
IPI: 通过物理相互作用推断
10629060 MGI
enables kinesin binding IDA
IDA: 通过直接分析推断
25944905 MGI
enables kinesin binding IPI
IPI: 通过物理相互作用推断
10629060 MGI
enables mitogen-activated protein kinase kinase binding IPI
IPI: 通过物理相互作用推断
10523642 MGI
enables mitogen-activated protein kinase kinase kinase binding IPI
IPI: 通过物理相互作用推断
10523642 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10523642 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within JNK cascade IDA
IDA: 通过直接分析推断
10629060 MGI
involved in anterograde axonal protein transport IMP
IMP: 通过突变表型推断
28259553 MGI
involved in axon development IMP
IMP: 通过突变表型推断
23576431 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
15572149 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
12897243 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
18324732 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
18324732 MGI
acts upstream of or within lung morphogenesis IMP
IMP: 通过突变表型推断
18324732 MGI
acts upstream of or within positive regulation of JUN kinase activity IDA
IDA: 通过直接分析推断
15767678 MGI
involved in positive regulation of JUN kinase activity IDA
IDA: 通过直接分析推断
10523642 MGI
involved in positive regulation of neuron migration IMP
IMP: 通过突变表型推断
28259553 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
18324732 MGI
acts upstream of or within protein localization IMP
IMP: 通过突变表型推断
15572149 MGI
involved in regulation of JNK cascade IDA
IDA: 通过直接分析推断
10629060 MGI
acts upstream of or within regulation of gene expression IDA
IDA: 通过直接分析推断
18324732 MGI
acts upstream of or within respiratory gaseous exchange by respiratory system IMP
IMP: 通过突变表型推断
12897243 MGI
involved in vesicle-mediated transport IDA
IDA: 通过直接分析推断
11106729 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi membrane IDA
IDA: 通过直接分析推断
11106729 MGI
located in axolemma IDA
IDA: 通过直接分析推断
16606357 MGI
located in axon IDA
IDA: 通过直接分析推断
25944905 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
10523642 MGI
located in dendrite IDA
IDA: 通过直接分析推断
16606357 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16606357 MGI
located in smooth endoplasmic reticulum IDA
IDA: 通过直接分析推断
16606357 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-Jun-amino-terminal kinase-interacting protein 3

JNK MAP kinase scaffold protein 3

JNK-interacting protein 3

JNK/SAPK-associated protein 1

JNK/SAPK-associated protein 1c

JUN/SAPK-associated protein 1

c-Jun NH2-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1

sunday driver

Mapk8ip3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Mapk8ip3 Q9ESN9 Kif5c Mus musculus P28738
Pull Down
21750526
种属内
Mapk8ip3 Q9ESN9 Klc1 Mus musculus O88447
CoIP
11106729
种属内
Mapk8ip3 Q9ESN9 Klc1 Mus musculus O88447
Pull Down
11106729
种属内
Mapk8ip3 Q9ESN9 Klc1 Mus musculus O88447
Pull Down
21750526
种属内
Mapk8ip3 Q9ESN9 Klc2 Mus musculus O88448
Pull Down
11106729
种属内
Mapk8ip3 Q9ESN9 Klc2 Mus musculus O88448
CoIP
11106729
种属内
Mapk8ip3 Q9ESN9 Klc2 Mus musculus O88448
Pull Down
21750526
种属内
Mapk8ip3 Q9ESN9 Arf6 Mus musculus P62331
Anti Tag CoIP
20493856
种属内
Mapk8ip3 Q9ESN9 Arf6 Mus musculus P62331
Pull Down
20493856
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08126 MAPK8IP3 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mapk8ip3 NCBI NCBI:23162
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