2. Gene
  3. Lpl - lipoprotein lipase Gene

Lpl - lipoprotein lipase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 16956 | 基因类型: protein coding

关于 Lpl

功能概要

Enables lipoprotein Lipase activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of macrophage derived foam cell differentiation; and triglyceride catabolic process. Acts upstream of or within response to bacterium. Located in cell surface and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; limb; lung; and sensory organ. Used to study familial lipoprotein Lipase deficiency. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); familial hyperlipidemia (multiple); muscular disease; and type 2 diabetes mellitus. Orthologous to human LPL (lipoprotein Lipase). [provided by Alliance of Genome Resources, Apr 2022]

Lpl 基因产物(1)

mRNA Protein Name
NM_008509.2 NP_032535.2 lipoprotein lipase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lipoprotein lipase activity IDA
IDA: 通过直接分析推断
2563260 MGI
enables triacylglycerol lipase activity IDA
IDA: 通过直接分析推断
15178420 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to fatty acid IDA
IDA: 通过直接分析推断
21986524 MGI
involved in cellular response to nutrient IDA
IDA: 通过直接分析推断
21986524 MGI
involved in positive regulation of chemokine (C-X-C motif) ligand 2 production IGI
IGI: 通过遗传相互作用推断
22963823 MGI
involved in positive regulation of inflammatory response IGI
IGI: 通过遗传相互作用推断
22963823 MGI
involved in positive regulation of interleukin-1 beta production IGI
IGI: 通过遗传相互作用推断
22963823 MGI
involved in positive regulation of interleukin-6 production IGI
IGI: 通过遗传相互作用推断
22963823 MGI
involved in positive regulation of macrophage derived foam cell differentiation IGI
IGI: 通过遗传相互作用推断
10858435 MGI
involved in positive regulation of tumor necrosis factor production IGI
IGI: 通过遗传相互作用推断
22963823 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
involved in triglyceride catabolic process IDA
IDA: 通过直接分析推断
15178420 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
20620994 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
15178420 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lipoprotein lipase

O 1-4-5

phospholipase A1

相关产品

Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-P2752 Lipoprotein lipase, Pseudomonas sp / Phase 3
HY-117549 Ibrolipim Activator 99.48% Phase 2
HY-119741 Salacinol Inhibitor / Phase 2
Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P4153 Enlicitide chloride Inhibitor 99.63% 否
HY-N5015 Rosmanol Inhibitor 98.70% 否
HY-101395A W146 TFA 98.22% 否
HY-116538 (10E,12Z)-Octadeca-10,12-dienoic acid Activator 99.10% 否
HY-128671 6-​Thioinosine 99.31% 否
HY-165607S MCB-22-174 99.78% 否
HY-RS07563 LCP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07772 LPL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W040176 N-PTyrosine PA ammonium Inhibitor / 否
HY-RS17184 Lpl Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23635 Lpl Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lpl NCBI NCBI:4023
Macaca fascicularis Lpl NCBI NCBI:102129758
Rattus norvegicus Lpl NCBI NCBI:24539
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