2. Gene
  3. Ppp1r15a - protein phosphatase 1, regulatory subunit 15A Gene

Ppp1r15a - protein phosphatase 1, regulatory subunit 15A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gadd34; Myd116; 9630030H21

基因 ID: 17872 | 基因类型: protein coding

关于 Ppp1r15a

功能概要

Enables protein Phosphatase binding activity and protein Phosphatase regulator activity. Involved in several processes, including peptidyl-serine dephosphorylation; regulation of gene expression; and regulation of protein modification process. Acts upstream of or within endoplasmic reticulum unfolded protein response. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and mitochondrion. Predicted to be part of protein Phosphatase type 1 complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and liver. Used to study thalassemia. Orthologous to human PPP1R15A (protein Phosphatase 1 regulatory subunit 15A). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1r15a 基因产物(1)

mRNA Protein Name
NM_008654.2 NP_032680.1 protein phosphatase 1 regulatory subunit 15A
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein phosphatase binding IDA
IDA: 通过直接分析推断
11381086 MGI
enables protein phosphatase regulator activity IDA
IDA: 通过直接分析推断
11381086 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within endoplasmic reticulum unfolded protein response IMP
IMP: 通过突变表型推断
15601821 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11381086 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
14635196 MGI
involved in positive regulation of peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
14635196 MGI
involved in positive regulation of transcription by RNA polymerase I IDA
IDA: 通过直接分析推断
14635196 MGI
involved in regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IDA
IDA: 通过直接分析推断
11381086 MGI
involved in response to endoplasmic reticulum stress IDA
IDA: 通过直接分析推断
11381086 MGI
involved in response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
15601821 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein phosphatase 1 regulatory subunit 15A

growth arrest and DNA damage-inducible protein GADD34

growth arrest and DNA-damage-inducible 34

myeloid differentiation primary response gene 116

myeloid differentiation primary response protein MyD116

protein phosphatase 1, regulatory (inhibitor) sub

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-111022 Icerguastat Inhibitor 99.93% Phase 2
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-18956 (E/Z)-Icerguastat Inhibitor 99.44% 否
HY-110365 Icerguastat Carbonate Inhibitor / 否
HY-18956B (E/Z)-Icerguastat acetate Inhibitor / 否
HY-RS10986 PPP1R15A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-18956A (E/Z)-Icerguastat hydrochloride Inhibitor / 否
HY-RS17569 Ppp1r15a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24029 Ppp1r15a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppp1r15a NCBI NCBI:23645
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