2. Gene
  3. Nlk - nemo like kinase Gene

Nlk - nemo like kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 18099 | 基因类型: protein coding

关于 Nlk

功能概要

Enables several functions, including ATP binding activity; SH2 domain binding activity; and magnesium ion binding activity. Involved in several processes, including intracellular signal transduction; negative regulation of Wnt signaling pathway; and protein phosphorylation. Acts upstream of or within protein autophosphorylation. Located in nucleus. Is expressed in several structures, including early embryo; genitourinary system; nervous system; neural retina; and respiratory system. Orthologous to human NLK (nemo like kinase). [provided by Alliance of Genome Resources, Apr 2022]

Nlk 基因产物(1)

mRNA Protein Name
NM_008702.3 NP_032728.3 serine/threonine-protein kinase NLK
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
9448268 MGI
enables MAP kinase activity IDA
IDA: 通过直接分析推断
9448268 MGI
enables SH2 domain binding IPI
IPI: 通过物理相互作用推断
15004007 MGI
enables magnesium ion binding IDA
IDA: 通过直接分析推断
9448268 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15082531 MGI
enables protein kinase activity IDA
IDA: 通过直接分析推断
9448268 MGI
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
15004007 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
9448268 MGI
involved in negative regulation of Wnt signaling pathway IMP
IMP: 通过突变表型推断
15082531 MGI
involved in peptidyl-threonine phosphorylation IDA
IDA: 通过直接分析推断
17785444 MGI
involved in positive regulation of receptor signaling pathway via STAT IDA
IDA: 通过直接分析推断
15004007 MGI
acts upstream of or within protein autophosphorylation IDA
IDA: 通过直接分析推断
9448268 MGI
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
9448268 MGI
involved in regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
14720327 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9448268 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase NLK

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148063 DB0614 98.80% 否
HY-148061 DB1113 99.22% 否
HY-RS05639 GPI Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09344 NLK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17483 Nlk Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23184 Gpi Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23941 Nlk Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nlk NCBI NCBI:51701
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