2. Gene
  3. Ppp3r1 - protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) Gene

Ppp3r1 - protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cnb1; CaNB1; MCIP1

基因 ID: 19058 | 基因类型: protein coding

关于 Ppp3r1

功能概要

Enables Phosphatase binding activity and phosphoprotein Phosphatase activity. Involved in postsynaptic modulation of chemical synaptic transmission and regulation of postsynaptic neurotransmitter receptor internalization. Acts upstream of or within several processes, including animal organ development; branching involved in blood vessel morphogenesis; and calcineurin-NFAT signaling cascade. Located in several cellular components, including Schaffer collateral - CA1 synapse; parallel fiber to Purkinje cell synapse; and sarcolemma. Part of Calcineurin complex. Is active in synapse. Is expressed in brain; heart; jaw skeleton; and tooth. Used to study dilated cardiomyopathy and schizophrenia. Human ortholog(s) of this gene implicated in Alzheimer's disease and dilated cardiomyopathy. Orthologous to human PPP3R1 (protein Phosphatase 3 regulatory subunit B, alpha). [provided by Alliance of Genome Resources, Apr 2022]

Ppp3r1 基因产物(1)

mRNA Protein Name
NM_024459.2 NP_077779.2 calcineurin subunit B type 1
蛋白主名 其他名称

calcineurin subunit B type 1

PP2B beta 1

protein phosphatase 2B regulatory subunit 1

protein phosphatase 3 regulatory subunit B alpha

Ppp3r1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ppp3r1 Q63810 Map3k5 Mus musculus O35099
Y2H
16648474
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11026 PPP3R1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21913 Ppp3r1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28430 Ppp3r1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppp3r1 NCBI NCBI:5534
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