2. Gene
  3. Frzb - frizzled-related protein Gene

Frzb - frizzled-related protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Frp; Sfrp3; fritz; frzb-1; frezzled

基因 ID: 20378 | 基因类型: protein coding

关于 Frzb

功能概要

Enables Wnt-protein binding activity. Involved in negative regulation of Wnt signaling pathway. Acts upstream of or within several processes, including animal organ development; negative regulation of cartilage development; and negative regulation of cell differentiation. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and skeleton. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human FRZB (Frizzled related protein). [provided by Alliance of Genome Resources, Apr 2022]

Frzb 基因产物(1)

mRNA Protein Name
NM_011356.4 NP_035486.1 secreted frizzled-related protein 3 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IDA
IDA: 通过直接分析推断
9178261 MGI
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
17462603 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9096311 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cochlea morphogenesis IGI
IGI: 通过遗传相互作用推断
17433286 MGI
acts upstream of or within convergent extension involved in organogenesis IGI
IGI: 通过遗传相互作用推断
17433286 MGI
acts upstream of epithelial cell development IDA
IDA: 通过直接分析推断
19562671 MGI
acts upstream of hepatocyte differentiation IDA
IDA: 通过直接分析推断
19562671 MGI
acts upstream of or within inner ear morphogenesis IDA
IDA: 通过直接分析推断
18991062 MGI
acts upstream of or within inner ear morphogenesis IGI
IGI: 通过遗传相互作用推断
18991062 MGI
involved in negative regulation of Wnt signaling pathway IDA
IDA: 通过直接分析推断
9178261 MGI
acts upstream of or within negative regulation of Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
17433286 MGI
acts upstream of or within negative regulation of canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
19961844 MGI
acts upstream of or within negative regulation of cartilage development IGI
IGI: 通过遗传相互作用推断
18991062 MGI
acts upstream of or within negative regulation of cell development IDA
IDA: 通过直接分析推断
19562671 MGI
acts upstream of or within negative regulation of hepatocyte differentiation IDA
IDA: 通过直接分析推断
19562671 MGI
involved in neural crest cell differentiation IEP
IEP: 通过表达模式推断
10654605 MGI
involved in somite development IEP
IEP: 通过表达模式推断
10654605 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

secreted frizzled-related protein 3

frizzled-related protein 1

secreted frizzled-related sequence protein 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05116 FRZB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19333 Frzb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25824 Frzb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Frzb NCBI NCBI:2487
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