2. Gene
  3. Top2b - topoisomerase (DNA) II beta Gene

Top2b - topoisomerase (DNA) II beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Top-2; D230016L12Rik

基因 ID: 21974 | 基因类型: protein coding

关于 Top2b

功能概要

Predicted to enable several functions, including enzyme binding activity; protein C-terminus binding activity; and protein heterodimerization activity. Acts upstream of or within axonogenesis; forebrain development; and neuron migration. Located in nucleus. Is expressed in central nervous system; genitourinary system; and retina. Orthologous to human TOP2B (DNA Topoisomerase II beta). [provided by Alliance of Genome Resources, Apr 2022]

Top2b 基因产物(1)

mRNA Protein Name
NM_009409.3 NP_033435.2 DNA topoisomerase 2-beta
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IMP
IMP: 通过突变表型推断
31409799 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21186367 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell differentiation IMP
IMP: 通过突变表型推断
31409799 MGI
acts upstream of or within axonogenesis IMP
IMP: 通过突变表型推断
10615047 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
12773624 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
12773624 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
NOT located in chromosome IDA
IDA: 通过直接分析推断
11835579 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9224616 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA topoisomerase 2-beta

DNA topoisomerase II, beta isozyme

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-174374 Topobexin Inhibitor 99.04% 否
HY-RS14897 TOP2B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-123393 PNU-142586 Inhibitor / 否
HY-175834 DNA/TOP2A-IN-1 / 否
HY-RS20119 Top2b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26623 Top2b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Top2b NCBI NCBI:7155
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z