1. Gene
  2. Ucp3 - uncoupling protein 3 (mitochondrial, proton carrier) Gene

Ucp3 - uncoupling protein 3 (mitochondrial, proton carrier) Gene

种属: Mus musculus

同用名: UCP-3; Slc25a9

基因 ID: 22229 | 基因类型: protein coding

关于 Ucp3

功能概要

Enables Oxidative Phosphorylation uncoupler activity. Acts upstream of or within fatty acid metabolic process and response to superoxide. Located in mitochondrion. Is expressed in adipose tissue; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Ucp3 基因产物(1)

mRNA Protein Name
NM_009464.3 NP_033490.1 mitochondrial uncoupling protein 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables oxidative phosphorylation uncoupler activity IMP
IMP: 通过突变表型推断
11707458 MGI
enables oxidative phosphorylation uncoupler activity IMP
IMP: 通过突变表型推断
10748195 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
26915802 MGI
enables proton transmembrane transporter activity IDA
IDA: 通过直接分析推断
29212043 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within fatty acid metabolic process IMP
IMP: 通过突变表型推断
10748196 MGI
involved in lipid hydroperoxide transport IMP
IMP: 通过突变表型推断
20363757 MGI
involved in proton transmembrane transport IDA
IDA: 通过直接分析推断
29212043 MGI
acts upstream of or within response to superoxide IMP
IMP: 通过突变表型推断
11780125 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
26915802 MGI
located in mitochondrion IMP
IMP: 通过突变表型推断
11707458 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

mitochondrial uncoupling protein 3

solute carrier family 25 member 9

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ucp3 NCBI NCBI:7352