2. Gene
  3. A2m - alpha-2-macroglobulin Gene

A2m - alpha-2-macroglobulin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: A2mp

基因 ID: 232345 | 基因类型: protein coding

关于 A2m

功能概要

Predicted to enable several functions, including cytokine binding activity; growth factor binding activity; and serine-type endopeptidase inhibitor activity. Acts upstream of or within stem cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; embryo mesenchyme; liver; meninges; and retina. Human ortholog(s) of this gene implicated in COVID-19; background diabetic retinopathy; multiple sclerosis; neurodegenerative disease (multiple); and obstructive lung disease. Orthologous to human A2M (alpha-2-macroglobulin). [provided by Alliance of Genome Resources, Apr 2022]

A2m 基因产物(1)

mRNA Protein Name
NM_175628.3 NP_783327.2 alpha-2-macroglobulin-P precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17920016 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within stem cell differentiation IDA
IDA: 通过直接分析推断
19796622 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-2-macroglobulin-P

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00010 A2M Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-CE00893 2M2PE-CoA / 否
HY-E70525A Alpha 2 Macroglobulin, Human Plasma, Fast Form Inhibitor / 否
HY-RS18322 A2m Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19112 Pzp Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24800 A2m Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens A2m NCBI NCBI:2
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