1. Metabolic Enzyme/Protease
  2. Proteasome
  3. Alpha 2 Macroglobulin, Human Plasma, Fast Form

Alpha 2 Macroglobulin, Human Plasma, Fast Form  (Synonyms: 快速型α2巨球蛋白,人血浆)

目录号: HY-E70525A
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Alpha 2 Macroglobulin, Human Plasma, Fast Form 是一种广谱蛋白酶抑制剂,是 Alpha 2 Macroglobulin 的快速形式 (Fast Form)。Alpha 2 Macroglobulin 还有一种慢速形式 (Slow Form)。慢速形式 Alpha 2 Macroglobulin 能够将活性蛋白酶引诱到其分子笼中,随后“标记”其复合物并进行消除。快速形式 Alpha 2 Macroglobulin 是慢速形式的变构产物,当蛋白酶被 A2M 诱饵区捕获,诱饵区附近的内部硫醇酯键发生化学裂解产生。Alpha 2 Macroglobulin 还促进细胞迁移以及细胞因子、生长因子和受损细胞外蛋白的结合。Alpha 2 Macroglobulin 在炎症、免疫和感染领域均有研究意义。

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Alpha 2 Macroglobulin, Human Plasma, Fast Form

Alpha 2 Macroglobulin, Human Plasma, Fast Form Chemical Structure

CAS No. : 403067-13-0

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生物活性

Alpha 2 Macroglobulin, Human Plasma, Fast Form is a broad-spectrum protease inhibitor, representing the fast form (Fast Form) of Alpha 2 Macroglobulin. Alpha 2 Macroglobulin also has a slow form (Slow Form). The slow form of Alpha 2 Macroglobulin can lure active proteases into its molecular cage and subsequently "tag" its complex for elimination. The fast form of Alpha 2 Macroglobulin is an allosteric product of the slow form, generated when proteases are captured by A2M bait regions, leading to chemical cleavage of internal thioester bonds near the bait regions. Alpha 2 Macroglobulin also promotes cell migration and binds cytokines, growth factors, and damaged extracellular proteins. Alpha 2 Macroglobulin holds research significance in inflammation, immunity, and infection[1].

CAS 号
中文名称

快速型α2巨球蛋白,人血浆

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Alpha 2 Macroglobulin, Human Plasma, Fast Form 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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