2. Gene
  3. AK1 - Ak1 adenylate kinase 1 Gene

AK1 - Ak1 adenylate kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ak 1

基因 ID: 24183 | 基因类型: protein coding

关于 AK1

功能概要

Enables adenylate kinase activity. Contributes to phosphotransferase activity, phosphate group as acceptor. Involved in several processes, including nervous system development; nucleobase-containing small molecule metabolic process; and positive regulation of neuron maturation. Located in neuron projection; perinuclear region of cytoplasm; and sarcomere. Biomarker of middle cerebral artery infarction; myocardial infarction; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in congenital nonspherocytic hemolytic anemia and hemolytic anemia. Orthologous to human AK1 (adenylate kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

AK1 基因产物(1)

mRNA Protein Name
NM_024349.4 NP_077325.2 adenylate kinase isoenzyme 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables adenylate kinase activity IDA
IDA: 通过直接分析推断
8468325 RGD
contributes to phosphotransferase activity, phosphate group as acceptor IDA
IDA: 通过直接分析推断
19049516 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ADP biosynthetic process IDA
IDA: 通过直接分析推断
19049516 RGD
involved in AMP metabolic process IDA
IDA: 通过直接分析推断
19049516 RGD
involved in cerebellum development IEP
IEP: 通过表达模式推断
9920788 RGD
involved in inosine biosynthetic process IDA
IDA: 通过直接分析推断
19049516 RGD
involved in muscle organ development IEP
IEP: 通过表达模式推断
8468325 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
10101232 RGD
involved in olfactory bulb development IEP
IEP: 通过表达模式推断
9920788 RGD
involved in positive regulation of D-glucose transmembrane transport IMP
IMP: 通过突变表型推断
21059655 RGD
involved in positive regulation of neuron maturation IEP
IEP: 通过表达模式推断
9920788 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
17002673 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
10383487 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
10383487 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17058275 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
9648858 RGD
located in sarcomere IDA
IDA: 通过直接分析推断
12432079 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

adenylate kinase isoenzyme 1

ATP-AMP transphosphorylase 1

ATP:AMP phosphotransferase

adenylate kinase isoenzyme 1-like

adenylate monophosphate kinase

myokinase

重组 AK1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74427 Adenylate Kinase 1/AK1 Protein, Rat (His) P39069 (M1-K194) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-151262 JAK-IN-23 Inhibitor 98.88% 否
HY-101465 AK-1 Inhibitor 99.84% 否
HY-RS00505 AK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174999 JAK3-IN-18 Inhibitor / 否
HY-RS04242 EIF2AK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W587827 Thiamine triphosphoric acid ester / 否
HY-RS16851 Ak1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22002 Eif2ak1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23292 Ak1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28519 Eif2ak1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens AK1 NCBI NCBI:203
Macaca fascicularis AK1 NCBI NCBI:101867187
Mus musculus AK1 NCBI NCBI:11636
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