Il1b - interleukin 1 beta Gene

中文名称：白介素 1β

种属: Rattus norvegicus

同用名: IL-1F2

关于 Il1b

功能概要

该基因编码的蛋白可启动细胞因子活性。参与多个过程，包括细胞内信号转导的正向调节；基因表达的调节；和神经发生的调节。位于细胞外空间。用于研究多种疾病，包括动脉疾病（多种）；脑部疾病（多种）；肾小球肾炎（多发性）；间质性肺病（多发性）；和肾功能衰竭（多发）。多种疾病的生物标志物，包括动脉疾病（多种）；听觉系统疾病（多种）；脑部疾病（多种）；肾功能衰竭（多发）；和肺部疾病（多种）。该基因的人类直系同源物与多种疾病有关，包括自身免疫性疾病（多种）；血小板疾病（多发性）；眼病（多发）；胃肠系统癌症（多发性）；和肺部疾病（多种）。与人 IL1B（白细胞介素 1 β）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables cytokine activity. Involved in several processes, including positive regulation of intracellular signal transduction; regulation of gene expression; and regulation of neurogenesis. Located in extracellular space. Used to study several diseases, including artery disease (multiple); brain disease (multiple); glomerulonephritis (multiple); interstitial lung disease (multiple); and kidney failure (multiple). Biomarker of several diseases, including artery disease (multiple); auditory system disease (multiple); brain disease (multiple); kidney failure (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system Cancer (multiple); and lung disease (multiple). Orthologous to human IL1B (interleukin 1 beta). [provided by Alliance of Genome Resources, Apr 2022]