Ripk3 - receptor-interacting serine-threonine kinase 3 Gene

中文名称：受体相互作用的丝氨酸-苏氨酸激酶 3

种属: Rattus norvegicus

同用名: Rip3; Hcyp2

关于 Ripk3

功能概要

预计该基因编码的蛋白可启动 NF-kappaB 诱导激酶活性；相同的蛋白质结合活性；和蛋白丝氨酸/苏氨酸激酶活性。预计参与多个过程，包括造血或淋巴器官发育；坏死过程；磷酸盐代谢过程的正向调控。预计在几个过程的上游或内部起作用，包括 I-kappaB 激酶/NF-kappaB 信号；内在凋亡信号通路的正向调控；和蛋白质脱乙酰化的正调节。预测位于胞质溶胶和细胞核中。预计是含蛋白质复合物的一部分。预计在细胞质中有活性。与人 RIPK3（受体相互作用丝氨酸/苏氨酸激酶 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable NF-kappaB-inducing kinase activity; identical protein binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including hematopoietic or lymphoid organ development; necroptotic process; and positive regulation of phosphate metabolic process. Predicted to act upstream of or within several processes, including I-kappaB kinase/NF-kappaB signaling; positive regulation of intrinsic apoptotic signaling pathway; and positive regulation of protein deacetylation. Predicted to be located in cytosol and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2022]