2. Gene
  3. PDE4B - Pde4b phosphodiesterase 4B Gene

PDE4B - Pde4b phosphodiesterase 4B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pde4B1; Pde4B2; Pde4B3; Pde4B4; Pde4b5; PDE4/IVb; Pde4b_v1; Pde4b_v2; Pde4b_v3; Pde4b_v4

基因 ID: 24626 | 基因类型: protein coding

关于 PDE4B

功能概要

Enables 3',5'-cyclic-AMP phosphodiesterase activity. Involved in response to heat. Located in cytosol; nucleus; and perinuclear region of cytoplasm. Orthologous to human PDE4B (phosphodiesterase 4B). [provided by Alliance of Genome Resources, Apr 2022]

PDE4B 基因产物(2)

mRNA Protein Name
NM_001398935.1 NP_001385864.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1
NM_017031.3 NP_058727.3 cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3',5'-cyclic-AMP phosphodiesterase activity IDA
IDA: 通过直接分析推断
12441002 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15242814 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cAMP-specific 3',5'-cyclic phosphodiesterase 4B

3',5'-cyclic AMP phosphodiesterase

DPDE4

Phosphodiesterase 4B, cAMP-specific (dunce

phosphodiesterase 4B, cAMP specific

phosphodiesterase type 4B5

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-15455 Roflumilast Inhibitor 99.98% 是
Clinical Phase
生物活性分子 (11)
目录号 产品名 作用方式
纯度 Phase
HY-153192 Nerandomilast Inhibitor 99.93% Phase 3
HY-153192A Nerandomilast dihydrate Inhibitor 99.93% Phase 3
HY-16900 Rolipram Inhibitor 99.45% Phase 2
HY-10469 GSK256066 Inhibitor 98.69% Phase 2
HY-117960 Orismilast Inhibitor 99.88% Phase 2
HY-112831 Osoresnontrine Inhibitor 99.88% Phase 2
HY-70069 GSK256066 Trifluoroacetate Inhibitor 99.83% Phase 2
HY-144683 PF-07038124 Inhibitor / Phase 2
HY-111167 AN-2898 Inhibitor / Phase 2
HY-106003 GSK356278 Inhibitor 99.82% Phase 1
HY-131707 LEO 39652 Inhibitor 99.51% Phase 1
Pre-clinical Phase
生物活性分子 (35)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-128358 MR-L2 Activator 98.63% 否
HY-122942 Moracin M 98.99% 否
HY-115687 PDE4B-IN-2 Inhibitor 99.59% 否
HY-119190 PF-06445974 Inhibitor 98.59% 否
HY-16900A (R)-(-)-Rolipram Inhibitor 99.91% 否
HY-103050 ML-030 Inhibitor 99.50% 否
HY-139178 KVA-D-88 Inhibitor 99.81% 否
HY-100246 CI-1044 Inhibitor 98.02% 否
HY-144683A PF-07038124 hydrochloride Inhibitor 99.26% 否
HY-155830 Morcamilast Inhibitor 98.92% 否
HY-117977 FCPR03 Inhibitor 99.82% 否
HY-147830 PDE4B-IN-3 Inhibitor 99.37% 否
HY-115913 PDE4-IN-6 Inhibitor / 否
HY-121162 Mesembrine Inhibitor / 否
HY-144684 PDE4-IN-8 Inhibitor / 否
HY-146201 PDE4B/7A-IN-1 Antagonist / 否
HY-146202 PDE4B/7A-IN-2 / 否
HY-147950 PDE4-IN-10 Inhibitor / 否
HY-159654 PDE4-IN-19 Inhibitor / 否
HY-161851 MDL3 Inhibitor / 否
HY-162582 Z19153 Inhibitor / 否
HY-162583 PDE4-IN-17 Inhibitor / 否
HY-168558 PDE4B/D-IN-4 Inhibitor / 否
HY-172365 P7–2302 Inhibitor / 否
HY-172776 Phosphodiesterase-IN-3 Inhibitor / 否
HY-172870 PDE4B-IN-4 Inhibitor / 否
HY-174339 Neuroprotective agent 12 / 否
HY-174383 PDE3/4-IN-2 Inhibitor / 否
HY-175832 PDE4B-IN-5 Inhibitor / 否
HY-176520 PDE4-IN-29 Inhibitor / 否
HY-RS10223 PDE4B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-119799 UK-500001 Inhibitor / 否
HY-RS16654 Pde4b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23089 Pde4b Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-176524S PDE3/4-IN-3 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens PDE4B NCBI NCBI:5142
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