2. Gene
  3. PLA2G4A - Pla2g4a phospholipase A2 group IVA Gene

PLA2G4A - Pla2g4a phospholipase A2 group IVA Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pla2c; cPLA2; Pla2g4

基因 ID: 24653 | 基因类型: protein coding

关于 PLA2G4A

功能概要

Enables calcium-dependent Phospholipase A2 activity and Histone Acetyltransferase binding activity. Involved in several processes, including positive regulation of prostaglandin biosynthetic process; reproductive structure development; and surfactant homeostasis. Located in several cellular components, including cytosol; perinuclear region of cytoplasm; and zymogen granule. Used to study hyperglycemia. Biomarker of asthma; brain ischemia; papilloma; polycystic kidney disease; and transitional cell carcinoma. Orthologous to human PLA2G4A (Phospholipase A2 group IVA). [provided by Alliance of Genome Resources, Apr 2022]

PLA2G4A 基因产物(1)

mRNA Protein Name
NM_133551.2 NP_598235.2 cytosolic phospholipase A2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent phospholipase A2 activity IDA
IDA: 通过直接分析推断
8148815 RGD
enables histone acetyltransferase binding IPI
IPI: 通过物理相互作用推断
11416127 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in arachidonate metabolic process IMP
IMP: 通过突变表型推断
16603549 RGD
involved in cellular response to homocysteine IEP
IEP: 通过表达模式推断
31125437 RGD
involved in decidualization IMP
IMP: 通过突变表型推断
10050766 RGD
involved in luteolysis IEP
IEP: 通过表达模式推断
11444430 RGD
involved in ovulation from ovarian follicle IMP
IMP: 通过突变表型推断
10189070 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
15486059 RGD
involved in positive regulation of bone mineralization IEP
IEP: 通过表达模式推断
10807497 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17060404 RGD
involved in positive regulation of fever generation IEP
IEP: 通过表达模式推断
16933973 RGD
involved in positive regulation of prostaglandin biosynthetic process IMP
IMP: 通过突变表型推断
16203828 RGD
involved in positive regulation of vesicle fusion IMP
IMP: 通过突变表型推断
17148545 RGD
involved in response to calcium ion IMP
IMP: 通过突变表型推断
16828086 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
10092307 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
15368358 RGD
involved in response to hydrogen peroxide IEP
IEP: 通过表达模式推断
16864412 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
17093905 RGD
involved in response to methylmercury IEP
IEP: 通过表达模式推断
15019302 RGD
involved in response to vitamin D IEP
IEP: 通过表达模式推断
15225789 RGD
involved in surfactant homeostasis IMP
IMP: 通过突变表型推断
10025671 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15486059 RGD
located in zymogen granule IDA
IDA: 通过直接分析推断
17148545 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytosolic phospholipase A2

cytosolic phospholipase A2-like

phospholipase A2 cytosolic

phospholipase A2, group IVA (cytosolic, calcium-dependent)

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-18540 KT109 Inhibitor 99.86% 否
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10626 PLA2G4A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17434 Pla2g4a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23889 Pla2g4a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens PLA2G4A NCBI NCBI:5321
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