1. Gene
  2. Gcg - glucagon Gene

Gcg - glucagon Gene

种属: Rattus norvegicus

同用名: Glp1; GLP-1

基因 ID: 24952 | 基因类型: protein coding

关于 Gcg

功能概要

Enables Glucagon Receptor binding activity and hormone activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; negative regulation of appetite; and response to L-arginine. Located in extracellular space. Human ortholog(s) of this gene implicated in Alzheimer's disease and prediabetes syndrome. Orthologous to human GCG (glucagon). [provided by Alliance of Genome Resources, Apr 2022]

Gcg 基因产物(1)

mRNA Protein Name
NM_012707.3 NP_036839.2 pro-glucagon preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glucagon receptor binding IDA
IDA: 通过直接分析推断
12960094 RGD
enables hormone activity IDA
IDA: 通过直接分析推断
12960094 RGD
enables hormone activity IMP
IMP: 通过突变表型推断
11557638 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
12960094 RGD
involved in negative regulation of appetite IMP
IMP: 通过突变表型推断
11557638 RGD
involved in response to L-arginine IEP
IEP: 通过表达模式推断
2182011 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12876072 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pro-glucagon

glucagon-like peptide-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gcg NCBI NCBI:2641
Mus musculus Gcg NCBI NCBI:14526