1. Gene
  2. Chrm4 - cholinergic receptor, muscarinic 4 Gene

Chrm4 - cholinergic receptor, muscarinic 4 Gene

种属: Rattus norvegicus

同用名: M4

基因 ID: 25111 | 基因类型: protein coding

关于 Chrm4

功能概要

Enables guanyl-nucleotide exchange factor activity. Involved in response to organic substance. Located in several cellular components, including axon terminus; neuronal cell body; and postsynaptic density. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane and integral component of presynaptic membrane. Colocalizes with sarcolemma. Biomarker of congestive heart failure. Orthologous to human CHRM4 (cholinergic receptor muscarinic 4). [provided by Alliance of Genome Resources, Apr 2022]

Chrm4 基因产物(1)

mRNA Protein Name
NM_031547.1 NP_113735.1 muscarinic acetylcholine receptor M4
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables guanyl-nucleotide exchange factor activity IDA
IDA: 通过直接分析推断
12048193 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12048193 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in asymmetric synapse IDA
IDA: 通过直接分析推断
8182478 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
8182478 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
8182478 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12048193 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
8182478 RGD
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
8182478 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
15961389 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

muscarinic acetylcholine receptor M4

cholinergic receptor, muscarin 4

Chrm4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Chrm4 P08485 Camk2a Rattus norvegicus P11275 20461055
种属内
Chrm4 P08485 Camk2a Rattus norvegicus P11275 20461055
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrm4 NCBI NCBI:1132