CHRM4 - cholinergic receptor muscarinic 4 Gene

中文名称：胆碱能受体毒蕈碱 4

种属: Homo sapiens

同用名: HM4; M4R

关于 CHRM4

功能概要

毒蕈碱性胆碱能受体属于更大的 G 蛋白偶联受体家族。这些受体的功能多样性由乙酰胆碱的结合定义，包括腺苷酸环化酶抑制、磷酸肌醇变性和钾通道介导等细胞反应。毒蕈碱受体影响乙酰胆碱在中枢和周围神经系统中的许多作用。该受体的临床意义尚不清楚；然而，小鼠研究将其功能与腺苷酸环化酶抑制联系起来。[RefSeq 提供，2008 年 7 月]

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as Adenylate Cyclase inhibition, phosphoinositide degeneration, and Potassium Channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]