1. Gene
  2. Socs1 - suppressor of cytokine signaling 1 Gene

Socs1 - suppressor of cytokine signaling 1 Gene

种属: Rattus norvegicus

同用名: Cish1; Socs-1

基因 ID: 252971 | 基因类型: protein coding

关于 Socs1

功能概要

Predicted to enable insulin-like growth factor receptor binding activity; kinase regulator activity; and protein kinase binding activity. Involved in several processes, including response to estradiol; response to lipopolysaccharide; and response to progesterone. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Biomarker of myocardial infarction and obesity. Human ortholog(s) of this gene implicated in ovarian carcinoma; prostate cancer; and urinary bladder Cancer. Orthologous to human SOCS1 (suppressor of cytokine signaling 1). [provided by Alliance of Genome Resources, Apr 2022]

Socs1 基因产物(1)

mRNA Protein Name
NM_145879.2 NP_665886.2 suppressor of cytokine signaling 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
11867182 RGD
acts upstream of or within cellular response to cytokine stimulus IDA
IDA: 通过直接分析推断
19414010 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
21742974 RGD
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: 通过直接分析推断
19414010 RGD
involved in cellular response to thyrotropin-releasing hormone IEP
IEP: 通过表达模式推断
10707961 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
10707961 RGD
involved in cellular response to vascular endothelial growth factor stimulus IEP
IEP: 通过表达模式推断
30771456 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
18424750 RGD
involved in response to erythropoietin IEP
IEP: 通过表达模式推断
22796671 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
18325991 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18424750 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
18325991 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
18325991 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
18171911 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

suppressor of cytokine signaling 1

cytokine inducible SH2-containing protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Socs1 NCBI NCBI:8651