2. Gene
  3. Tnfrsf11b - TNF receptor superfamily member 11B Gene

Tnfrsf11b - TNF receptor superfamily member 11B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Opg

基因 ID: 25341 | 基因类型: protein coding

关于 Tnfrsf11b

功能概要

Predicted to enable cytokine activity. Involved in several processes, including negative regulation of bone resorption; negative regulation of odontogenesis of dentin-containing tooth; and response to estrogen. Located in extracellular space. Biomarker of congestive heart failure; myocarditis; and periapical periodontitis. Human ortholog(s) of this gene implicated in Paget's disease of bone and osteoarthritis. Orthologous to human TNFRSF11B (TNF Receptor Superfamily member 11b). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf11b 基因产物(1)

mRNA Protein Name
NM_012870.2 NP_037002.1 tumor necrosis factor receptor superfamily member 11B precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of bone resorption IDA
IDA: 通过直接分析推断
16912914 RGD
involved in negative regulation of bone resorption IMP
IMP: 通过突变表型推断
11839361 RGD
involved in negative regulation of odontogenesis of dentin-containing tooth IEP
IEP: 通过表达模式推断
16283633 RGD
involved in response to arsenic-containing substance IEP
IEP: 通过表达模式推断
17190191 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
16624776 RGD
involved in response to magnesium ion IEP
IEP: 通过表达模式推断
16162295 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
16696921 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16696922 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
22353912 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor receptor superfamily member 11B

Osteoprotegerin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14802 TNFRSF11B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17571 Tnfrsf11b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24031 Tnfrsf11b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnfrsf11b NCBI NCBI:4982
Mus musculus Tnfrsf11b NCBI NCBI:18383
Macaca mulatta Tnfrsf11b NCBI NCBI:701850
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