2. Gene
  3. Il17f - interleukin 17F Gene

Il17f - interleukin 17F Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IL-17F

基因 ID: 257630 | 基因类型: protein coding

关于 Il17f

功能概要

Enables cytokine receptor binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in defense response to bacterium and positive regulation of gene expression. Acts upstream of or within positive regulation of cytokine production involved in inflammatory response and positive regulation of transcription by RNA polymerase II. Located in extracellular space. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis. Orthologous to human IL17F (interleukin 17F). [provided by Alliance of Genome Resources, Apr 2022]

Il17f 基因产物(1)

mRNA Protein Name
NM_145856.2 NP_665855.2 interleukin-17F precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine receptor binding IPI
IPI: 通过物理相互作用推断
17911633 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18025225 MGI
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
18025225 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
18025225 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in defense response to Gram-negative bacterium IMP
IMP: 通过突变表型推断
19144317 MGI
involved in defense response to Gram-positive bacterium IMP
IMP: 通过突变表型推断
19144317 MGI
involved in positive regulation of antimicrobial peptide production IDA
IDA: 通过直接分析推断
19144317 MGI
acts upstream of or within positive regulation of cytokine production involved in inflammatory response IDA
IDA: 通过直接分析推断
16785495 MGI
acts upstream of or within positive regulation of cytokine production involved in inflammatory response IGI
IGI: 通过遗传相互作用推断
16785495 MGI
involved in positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
20554964 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16982811 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16982811 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17982105 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interleukin-17F

重组 Il17f 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72584 IL-17F Protein, Mouse (HEK293, His) Q7TNI7-1 (R29-A161) ≥95%
HY-P74831 IL-17F Protein, Mouse Q7TNI7-1 (R21-A153) ≥95%
HY-P77707 IL-17A/F Heterodimer Protein, Mouse (HEK293, His-Avi) Q62386 (A26-A158)&Q7TNI7 (R29-A161) ≥95%
HY-P77708 IL-17A/F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi) Q62386 (A26-A158)&Q7TNI7-1 (R29-A161) ≥95%
HY-P78160 IL-17F Protein, Mouse (Biotinylated, HEK293, His-Avi) Q7TNI7-1 (R29-A161) ≥95%
HY-P78321 IL-17F Protein, Mouse (HEK293, His-Avi) Q7TNI7-1 (R29-A161) ≥95%
HY-P700195AF Animal-Free IL-17F Protein, Mouse (His) Q7TNI7-1 (R29-A161) ≥95%

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P99280 Bimekizumab Antagonist 99.00% 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-152851 Izumerogant Agonist 99.95% Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99397 Sonelokimab Inhibitor 99.81% Phase 3
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-124686 ER-464195-01 Inhibitor / 否
HY-153276 Androgen receptor-IN-5 Inhibitor / 否
HY-168971 Paeoniflorin-6′-O-benzene sulfonate / 否
HY-RS06701 IL17F Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17703 Il17f Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24167 Il17f Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99424 Afasevikumab Inhibitor 95% 否
HY-P991146 Lecankitug Ligand / 否
HY-P990221 Anti-Mouse IL-17F Antibody (MM17F8F5.1A9) Inhibitor ≥95.0% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il17f NCBI NCBI:112744
Macaca fascicularis Il17f NCBI NCBI:102118959
Rattus norvegicus Il17f NCBI NCBI:301291
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