2. Gene
  3. Slc7a11 - solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Gene

Slc7a11 - solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: sut; xCT; 9930009M05Rik

基因 ID: 26570 | 基因类型: protein coding

关于 Slc7a11

功能概要

Predicted to enable L-amino acid transmembrane transporter activity. Acts upstream of or within several processes, including animal organ development; oligopeptide transmembrane transport; and regulation of cellular amino acid metabolic process. Located in apical part of cell; astrocyte projection; and brush border membrane. Is expressed in brain; meninges; and sensory organ. Used to study Hermansky-Pudlak syndrome and platelet storage pool deficiency. Orthologous to human SLC7A11 (solute carrier family 7 member 11). [provided by Alliance of Genome Resources, Apr 2022]

Slc7a11 基因产物(1)

mRNA Protein Name
NM_011990.2 NP_036120.1 cystine/glutamate transporter
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-cystine transport IMP
IMP: 通过突变表型推断
16037214 MGI
acts upstream of or within L-glutamate import across plasma membrane IMP
IMP: 通过突变表型推断
21490221 MGI
acts upstream of or within adult behavior IDA
IDA: 通过直接分析推断
29024663 MGI
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
17035536 MGI
acts upstream of or within cellular response to oxidative stress IDA
IDA: 通过直接分析推断
17035536 MGI
acts upstream of or within cellular response to oxidative stress IMP
IMP: 通过突变表型推断
17035536 MGI
acts upstream of or within cellular response to stress IDA
IDA: 通过直接分析推断
29024663 MGI
acts upstream of or within dipeptide import across plasma membrane IMP
IMP: 通过突变表型推断
16037214 MGI
acts upstream of or within glutathione metabolic process IMP
IMP: 通过突变表型推断
17200146 MGI
acts upstream of or within glutathione transmembrane transport IDA
IDA: 通过直接分析推断
17035536 MGI
acts upstream of or within intracellular glutamate homeostasis IGI
IGI: 通过遗传相互作用推断
29024663 MGI
acts upstream of or within intracellular glutamate homeostasis IMP
IMP: 通过突变表型推断
21191088 MGI
acts upstream of or within limb development IMP
IMP: 通过突变表型推断
21490221 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
23085521 MGI
acts upstream of or within modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
25429150 MGI
acts upstream of or within platelet aggregation IMP
IMP: 通过突变表型推断
8699821 MGI
acts upstream of or within regulation of AMPA glutamate receptor clustering IMP
IMP: 通过突变表型推断
25429150 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: 通过突变表型推断
16037214 MGI
acts upstream of or within regulation of cellular response to oxidative stress IMP
IMP: 通过突变表型推断
16037214 MGI
acts upstream of or within regulation of cysteine metabolic process IMP
IMP: 通过突变表型推断
17200146 MGI
acts upstream of or within regulation of glutamate metabolic process IMP
IMP: 通过突变表型推断
21490221 MGI
acts upstream of or within regulation of glutathione biosynthetic process IMP
IMP: 通过突变表型推断
16037214 MGI
acts upstream of or within regulation of melanin biosynthetic process IMP
IMP: 通过突变表型推断
16037214 MGI
acts upstream of or within regulation of neutrophil apoptotic process IMP
IMP: 通过突变表型推断
17200146 MGI
acts upstream of or within regulation of protein transport IMP
IMP: 通过突变表型推断
16037214 MGI
acts upstream of or within regulation of synapse organization IMP
IMP: 通过突变表型推断
25429150 MGI
acts upstream of or within response to organic cyclic compound IMP
IMP: 通过突变表型推断
21191088 MGI
acts upstream of or within response to redox state IMP
IMP: 通过突变表型推断
16144837 MGI
acts upstream of or within striatum development IMP
IMP: 通过突变表型推断
17035536 MGI
acts upstream of or within ventricular system development IMP
IMP: 通过突变表型推断
17035536 MGI
acts upstream of or within visual learning IMP
IMP: 通过突变表型推断
21490221 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
16399997 MGI
located in astrocyte projection IDA
IDA: 通过直接分析推断
16399997 MGI
located in brush border membrane IDA
IDA: 通过直接分析推断
16399997 MGI
located in membrane IDA
IDA: 通过直接分析推断
29350434 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16399997 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cystine/glutamate transporter

amino acid transport system xc-

cysteine/glutamate transporter

sodium independent anionic amino acid transport system

solute carrier family 7 member 11

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0653A Levobupivacaine hydrochloride 99.86% 是
HY-B0653 Levobupivacaine / 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-W402682 SXC2023 Inhibitor 99.83% Phase 2
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15763 Erastin 99.76% 否
HY-W451275 HG106 Activator 99.95% 否
HY-149979 SLC7A11-IN-1 Inducer 97.06% 否
HY-RS13325 SLC7A11 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-169056 SLC7A11-IN-2 99.80% 否
HY-155851 Lepadin E / 否
HY-155852 Lepadin H Inducer / 否
HY-161075 Microtubule inhibitor 8 / 否
HY-176719 AKR1B1/STAT3/SLC7A11-regulator-1 / 否
HY-B0653AS Levobupivacaine-d9 hydrochloride / 否
HY-RS16551 Slc7a11 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22984 Slc7a11 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc7a11 NCBI NCBI:23657
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