2. Gene
  3. BRPF3 - bromodomain and PHD finger containing 3 Gene

BRPF3 - bromodomain and PHD finger containing 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含溴结构域和 PHD 指 3

种属: Homo sapiens

基因 ID: 27154 | 基因类型: protein coding

关于 BRPF3

Cytogenetic location: 6p21.31 Genomic coordinates (GRCh38): 6:36,196,744-36,232,790 (from NCBI)

This gene has 12 transcripts (splice variants), 287 orthologues and 8 paralogues. Ubiquitous expression in testis (RPKM 15.9), kidney (RPKM 10.5) and 25 other tissues.

功能概要

预测启用组蛋白结合活性。参与组蛋白 H3-K14 乙酰化和 DNA 复制的正调控。 MOZ/MORF 组蛋白乙酰转移酶复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable histone binding activity. Involved in histone H3-K14 acetylation and positive regulation of DNA replication. Part of MOZ/MORF Histone Acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

BRPF3 基因产物(7)

mRNA Protein Name
XM_047418649.1 XP_047274605.1 bromodomain and PHD finger-containing protein 3 isoform X1
XM_047418651.1 XP_047274607.1 bromodomain and PHD finger-containing protein 3 isoform X6
XM_011514492.2 XP_011512794.1 bromodomain and PHD finger-containing protein 3 isoform X5
XM_011514491.2 XP_011512793.1 bromodomain and PHD finger-containing protein 3 isoform X3
XM_011514490.2 XP_011512792.1 bromodomain and PHD finger-containing protein 3 isoform X2
XM_047418650.1 XP_047274606.1 bromodomain and PHD finger-containing protein 3 isoform X4
NM_015695.3 NP_056510.2 bromodomain and PHD finger-containing protein 3

BRPF3 蛋白结构

EPL1

EPL1: Enhancer of polycomb-like (48 - 194)

PHD_2

PHD_2: PHD-finger (227 - 259)

zf-HC5HC2H_2

zf-HC5HC2H_2: PHD-zinc-finger like domain (268 - 386)

Bromodomain

Bromodomain: Bromodomain (600 - 679)

PWWP

PWWP: PWWP domain (1075 - 1186)

  • 0
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  • 1205 a.a.
蛋白主名 其他名称

bromodomain and PHD finger-containing protein 3

关联疾病

疾病名称 别名
Lethal Congenital Contracture Syndrome 2

LCCS2

Lethal Congenital Contractural Syndrome 2

Multiple Contracture Syndrome, Israeli-Bedouin Type

Multiple Contracture Syndrome, Israeli Bedouin Type A

Multiple Contracture Syndrome, Israeli Bedouin Type

Lethal Congenital Contracture Syndrome Type 2

Israeli Bedouin Multiple Contracture Syndrome Type A

Contracture Syndrome, Lethal, Congenital, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107424 BAY-299 Inhibitor 99.24% 否
HY-101121 NI-42 Inhibitor 99.79% 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus BRPF3 VGNC VGNC:26573
Felis catus BRPF3 VGNC VGNC:60182
Rattus norvegicus BRPF3 RGD RGD:1306868
Macaca mulatta BRPF3 VGNC VGNC:70309
Mus musculus BRPF3 MGD MGI:2146836
Canis familiaris BRPF3 VGNC VGNC:38534
Others BRPF3 NCBI
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