2. Gene
  3. Axin2 - axin 2 Gene

Axin2 - axin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: axil; axin-2

基因 ID: 29134 | 基因类型: protein coding

关于 Axin2

功能概要

Enables beta-catenin binding activity and protein kinase binding activity. Involved in several processes, including negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; negative regulation of cell population proliferation; and positive regulation of protein kinase activity. Part of protein-containing complex. Human ortholog(s) of this gene implicated in colorectal Cancer and endometrial adenocarcinoma. Orthologous to human AXIN2 (axin 2). [provided by Alliance of Genome Resources, Apr 2022]

Axin2 基因产物(1)

mRNA Protein Name
NM_024355.1 NP_077331.1 axin-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-catenin binding IDA
IDA: 通过直接分析推断
9566905 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
9566905 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
23996200 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
19464575 RGD
involved in dorsal/ventral axis specification IDA
IDA: 通过直接分析推断
9566905 RGD
involved in negative regulation of Wnt signaling pathway IDA
IDA: 通过直接分析推断
9566905 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
15572025 RGD
involved in positive regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
23996200 RGD
involved in positive regulation of protein kinase activity IDA
IDA: 通过直接分析推断
9566905 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
22152883 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of protein-containing complex IDA
IDA: 通过直接分析推断
9566905 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

axin-2

axin-like protein

axis inhibition protein 2

conductin

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-123851 MSC2504877 Inhibitor 99.25% 否
HY-112799 DK419 Inhibitor 99.86% 否
HY-163767 Antitumor agent-171 Inhibitor 98.48% 否
HY-108516 TC-E 5001 Inhibitor / 否
HY-148918 E722-2648 Inhibitor / 否
HY-RS01292 AXIN2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20863 Axin2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27378 Axin2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991311 GSK3178022 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Axin2 NCBI NCBI:8313
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