2. Gene
  3. Hpca - hippocalcin Gene

Hpca - hippocalcin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29177 | 基因类型: protein coding

关于 Hpca

功能概要

Enables calcium ion binding activity and kinase binding activity. Involved in several processes, including activation of Phospholipase D activity; cellular response to electrical stimulus; and negative regulation of Guanylate Cyclase activity. Located in several cellular components, including dendrite; neuronal cell body membrane; and perikaryon. Is extrinsic component of membrane. Is active in glutamatergic synapse and postsynapse. Human ortholog(s) of this gene implicated in torsion dystonia 2. Orthologous to human HPCA (hippocalcin). [provided by Alliance of Genome Resources, Apr 2022]

Hpca 基因产物(1)

mRNA Protein Name
NM_017122.2 NP_058818.1 neuron-specific calcium-binding protein hippocalcin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
1543495 RGD
enables kinase binding IPI
IPI: 通过物理相互作用推断
23142228 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16470652 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of phospholipase D activity IDA
IDA: 通过直接分析推断
11211872 RGD
involved in calcium-mediated signaling IEP
IEP: 通过表达模式推断
20704590 RGD
involved in cellular response to L-glutamate IDA
IDA: 通过直接分析推断
20704590 RGD
involved in cellular response to electrical stimulus IEP
IEP: 通过表达模式推断
20704590 RGD
involved in negative regulation of guanylate cyclase activity IDA
IDA: 通过直接分析推断
15336960 RGD
involved in positive regulation of adenylate cyclase activity IDA
IDA: 通过直接分析推断
15336960 RGD
involved in positive regulation of phospholipase activity IDA
IDA: 通过直接分析推断
11211872 RGD
involved in positive regulation of protein targeting to membrane IDA
IDA: 通过直接分析推断
23142228 RGD
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: 通过直接分析推断
20852624 RGD
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: 通过突变表型推断
20852624 RGD
involved in response to Aroclor 1254 IEP
IEP: 通过表达模式推断
18602130 RGD
involved in response to L-glutamate IEP
IEP: 通过表达模式推断
20704590 RGD
involved in response to ketamine IEP
IEP: 通过表达模式推断
12614903 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18602130 RGD
involved in retina development in camera-type eye IEP
IEP: 通过表达模式推断
7789406 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
7789406 RGD
located in cytosol IDA
IDA: 通过直接分析推断
1543495 RGD
located in dendrite cytoplasm IDA
IDA: 通过直接分析推断
8233019 RGD
located in dendrite membrane IDA
IDA: 通过直接分析推断
8233019 RGD
located in dendritic spine head IDA
IDA: 通过直接分析推断
20704590 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20704590 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
20704590 RGD
located in membrane IDA
IDA: 通过直接分析推断
1543495 RGD
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
8233019 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
8233019 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
20704590 RGD
is active in postsynapse IMP
IMP: 通过突变表型推断
20704590 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuron-specific calcium-binding protein hippocalcin

P23K

calcium-binding protein

Hpca 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Hpca P84076 PDE1A Bos taurus P14100
Pull Down
16470652
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01791 CACNA1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06333 HPCA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17810 Hpca Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21232 Cacna1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24278 Hpca Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hpca NCBI NCBI:3208
Mus musculus Hpca NCBI NCBI:15444
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z