2. Gene
  3. Mag - myelin-associated glycoprotein Gene

Mag - myelin-associated glycoprotein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: 1B236

基因 ID: 29409 | 基因类型: protein coding

关于 Mag

功能概要

Enables carboxylic acid binding activity; protein kinase binding activity; and signaling receptor binding activity. Involved in several processes, including cellular response to mechanical stimulus; negative regulation of neuron differentiation; and regulation of neurogenesis. Located in several cellular components, including Schmidt-Lanterman incisure; mesaxon; and myelin sheath adaxonal region. Is integral component of plasma membrane. Used to study middle cerebral artery infarction and sciatic neuropathy. Biomarker of nerve compression syndrome. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 75. Orthologous to human MAG (myelin associated glycoprotein). [provided by Alliance of Genome Resources, Apr 2022]

Mag 基因产物(1)

mRNA Protein Name
NM_017190.4 NP_058886.1 myelin-associated glycoprotein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ganglioside GT1b binding IDA
IDA: 通过直接分析推断
8995428 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11733546 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
18381654 RGD
enables sialic acid binding IDA
IDA: 通过直接分析推断
8995428 RGD
enables sialic acid binding IMP
IMP: 通过突变表型推断
19420245 RGD
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
23132925 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell adhesion IDA
IDA: 通过直接分析推断
8995428 RGD
involved in cell-cell adhesion via plasma-membrane adhesion molecules IMP
IMP: 通过突变表型推断
9298990 RGD
involved in cellular response to mechanical stimulus IEP
IEP: 通过表达模式推断
16140204 RGD
involved in negative regulation of axon extension IMP
IMP: 通过突变表型推断
9298990 RGD
involved in negative regulation of neuron differentiation IDA
IDA: 通过直接分析推断
19349915 RGD
involved in negative regulation of neuron projection development IDA
IDA: 通过直接分析推断
15282288 RGD
involved in negative regulation of neuron projection development IMP
IMP: 通过突变表型推断
9298990 RGD
involved in nervous system development IEP
IEP: 通过表达模式推断
2464408 RGD
involved in positive regulation of astrocyte differentiation IDA
IDA: 通过直接分析推断
19349915 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Schmidt-Lanterman incisure IDA
IDA: 通过直接分析推断
12838505 RGD
located in mesaxon IDA
IDA: 通过直接分析推断
12838505 RGD
located in myelin sheath adaxonal region IDA
IDA: 通过直接分析推断
375239 RGD
located in plasma membrane IMP
IMP: 通过突变表型推断
9298990 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

myelin-associated glycoprotein

S-MAG (C-term.)

brain neuron cytoplasmic protein 3

sialic acid-binding Ig-like lectin 4a

siglec-4a

相关产品

Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-D1498 Mag-Fluo-4 AM ≥96.0% 否
HY-101898 Indo-1 AM 96% 否
HY-136924 FP-Biotin 99.84% 否
HY-10865 LY2183240 Inhibitor 98.01% 否
HY-112219A H3R antagonist 1 hydrochloride Inhibitor 99.10% 否
HY-P10369 Betiatide 98.91% 否
HY-112219 H3R antagonist 1 Inhibitor 99.21% 否
HY-146081 CD22 ligand-1 / 否
HY-D1700 Mag-indo-1/AM / 否
HY-D1701 Mag-Fura-2 AM / 否
HY-D1702 Mag-Fura-2 tetrapotassium / 否
HY-RS07963 MAG Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07976 MAGED1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07977 MAGED2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W127843 Mag-Indo-1 tetrapotassium salt / 否
HY-RS17016 Mag Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23459 Mag Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mag NCBI NCBI:4099
Mus musculus Mag NCBI NCBI:17136
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