1. Gene
  2. F8 - coagulation factor VIII Gene

F8 - coagulation factor VIII Gene

种属: Rattus norvegicus

基因 ID: 302470 | 基因类型: protein coding

关于 F8

功能概要

Predicted to enable copper ion binding activity and oxidoreductase activity. Involved in blood coagulation, intrinsic pathway. Located in extracellular space. Used to study Factor VIII deficiency; hemarthrosis; and hyperhomocysteinemia. Human ortholog(s) of this gene implicated in Factor VIII deficiency. Orthologous to human F8 (coagulation Factor VIII). [provided by Alliance of Genome Resources, Apr 2022]

F8 基因产物(1)

mRNA Protein Name
NM_183331.2 NP_899160.2 coagulation factor VIII precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in blood coagulation, intrinsic pathway IMP
IMP: 通过突变表型推断
2513867 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
2513867 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

coagulation factor VIII

coagulation factor VIII, procoagulant component

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F8 NCBI NCBI:2157
Felis catus F8 NCBI NCBI:101092751
Macaca fascicularis F8 NCBI NCBI:102125498
Mus musculus F8 NCBI NCBI:14069