2. Gene
  3. Dll4 - delta like canonical Notch ligand 4 Gene

Dll4 - delta like canonical Notch ligand 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 311332 | 基因类型: protein coding

关于 Dll4

功能概要

Predicted to enable Notch binding activity. Predicted to be involved in several processes, including cellular response to growth factor stimulus; circulatory system development; and regulation of Notch signaling pathway. Predicted to act upstream of or within angiogenesis; negative regulation of blood vessel endothelial cell migration; and regulation of neurogenesis. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human DLL4 (delta like canonical Notch ligand 4). [provided by Alliance of Genome Resources, Apr 2022]

Dll4 基因产物(1)

mRNA Protein Name
NM_001107760.1 NP_001101230.1 delta-like protein 4 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cholesterol IEP
IEP: 通过表达模式推断
28472949 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
30653356 RGD
involved in chondrocyte differentiation IEP
IEP: 通过表达模式推断
26872979 RGD
involved in luteolysis IEP
IEP: 通过表达模式推断
21209419 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

delta-like protein 4

delta-like 4

delta4

drosophila Delta homolog 4

相关产品

Clinical Phase
抗体抑制剂 (4)
目录号 产品名 作用方式
纯度 Phase
HY-P99377 Navicixizumab Inhibitor 99.83% Phase 3
HY-P99261 Demcizumab Inhibitor ≥95.0% Phase 2
HY-P99852 Dilpacimab Inhibitor / Phase 2
HY-P99925 Enoticumab Inhibitor 99.64% Phase 1
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122094 Steppogenin Inhibitor 99.49% 否
HY-RS03810 DLL4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16878 Dll4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23320 Dll4 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991033 Tovecimig / 否
HY-P990252 Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) / 否
HY-P991423 MEDI0639 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dll4 NCBI NCBI:54567
Mus musculus Dll4 NCBI NCBI:54485
Macaca mulatta Dll4 NCBI NCBI:704898
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