2. Neuronal Signaling Stem Cell/Wnt
  3. Notch
  4. Navicixizumab

Navicixizumab  (Synonyms: OMP-305B83; Anti-DLL4 Reference Antibody (navicixizumab))

目录号: HY-P99377

摩尔计算器

Navicixizumab (OMP-305B83) 是一种双特异性抗 VEGF 和抗 DLL4 抑制抗体。Navicixizumab 可以与紫杉醇结合用于癌症研究。Navicixizumab 可用于卵巢癌、原发性腹膜癌或输卵管癌的研究。

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Navicixizumab Chemical Structure

Navicixizumab Chemical Structure

CAS No. : 1638338-43-8

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Navicixizumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Navicixizumab (OMP-305B83) is a bispecific anti-VEGF and anti-DLL4 inhibitory antibody. Navicixizumab can combine with Paclitaxel.html" class="link-product" target="_blank"> Paclitaxel (HY-B0015) for cancer research. Navicixizumab can be used in the research of ovarian, primary peritoneal, or fallopian tube cancer[1][2][3].

IC50 & Target

IC50: hVEGF (0.36 nM), mVEGF (25.5 nM), hDLL4 (1.3 nM)
体外研究
(In Vitro)

Navicixizumab (0-100 μM) 在 hVEGF 存在的情况下减少人内皮细胞的增殖[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Navicixizumab 相关抗体:
体内研究
(In Vivo)

Navicixizumab (15 mg/kg，每周一次，持续 4 周) 抑制结肠异种移植肿瘤的生长[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Navicixizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Navicixizumab1638338-43-8OMP-305B83 Anti-DLL4 Reference Antibody (navicixizumab)NotchNavicixizumab (OMP-305B83) 是一种双特异性抗 VEGF 和抗 DLL4 抑制抗体。Navicixizumab 可以与紫杉醇结合用于癌症研究。Navicixizumab 可用于卵巢癌、原发性腹膜癌或输卵管癌的研究。Inhibitorinhibitorinhibit

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