2. Gene
  3. Gars - glycyl-tRNA synthetase Gene

Gars - glycyl-tRNA synthetase Gene

  • 基因
  • 蛋白
  • 相关产品

种属: Mus musculus

同用名: Gars1; Nmf249; Sgrp23; GENA202; Gena201

基因 ID: 353172 | 基因类型: protein coding

关于 Gars

功能概要

Enables glycine-tRNA Ligase activity. Acts upstream of or within glycyl-tRNA aminoacylation. Located in extracellular exosome and secretory granule. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; respiratory system; and urinary system. Used to study Charcot-Marie-Tooth disease type 2D. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. Orthologous to human GARS1 (glycyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Gars 基因产物(1)

mRNA Protein Name
NM_180678.3 NP_851009.2 glycine--tRNA ligase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glycine-tRNA ligase activity IMP
IMP: 通过突变表型推断
19470612 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8939962 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glycyl-tRNA aminoacylation IMP
IMP: 通过突变表型推断
19470612 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular exosome IDA
IDA: 通过直接分析推断
26503042 MGI
located in secretory granule IDA
IDA: 通过直接分析推断
8939962 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glycine--tRNA ligase

AP-4-A synthetase

ap4A synthetase

diadenosine tetraphosphate synthetase

glyRS

glycyl-tRNA synthetase 1

storage granule protein 23

相关产品

Approval
生物活性分子 (6)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0117 Tigecycline 99.95% 是
HY-B0117C Tigecycline tetramesylate 97.01% 是
HY-B0117D Tigecycline hydrate 99.51% 否
HY-B0117A Tigecycline hydrochloride / 否
HY-B0117B Tigecycline mesylate / 否
HY-B0117R Tigecycline (Standard) / 否
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-B0117S Tigecycline-d9 97.94% 否
HY-117058 LY243246 / 否
HY-14526 5-DACTHF Inhibitor / 否
HY-RS05277 GAR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05279 GARS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05280 GART Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19198 Gars1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25686 Gars1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
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