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  2. Atg5 - autophagy related 5 Gene

Atg5 - autophagy related 5 Gene

种属: Rattus norvegicus

基因 ID: 365601 | 基因类型: protein coding

关于 Atg5

功能概要

Involved in several processes, including chaperone-mediated autophagy; response to fluoride; and response to iron(II) ion. Located in axon. Part of protein-containing complex. Biomarker of ischemia. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 25. Orthologous to human ATG5 (Autophagy related 5). [provided by Alliance of Genome Resources, Apr 2022]

Atg5 基因产物(4)

mRNA Protein Name
NM_001014250.2 NP_001014272.1 autophagy protein 5 isoform 1
NM_001399019.1 NP_001385948.1 autophagy protein 5 isoform 2
NM_001399020.1 NP_001385949.1 autophagy protein 5 isoform 3
NM_001399021.1 NP_001385950.1 autophagy protein 5 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18059433 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in autophagosome assembly IMP
IMP: 通过突变表型推断
16420522 RGD
involved in autophagy IMP
IMP: 通过突变表型推断
18059433 RGD
involved in chaperone-mediated autophagy IMP
IMP: 通过突变表型推断
23434281 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
20075199 RGD
involved in positive regulation of autophagy IMP
IMP: 通过突变表型推断
30715741 RGD
involved in positive regulation of stress granule assembly IMP
IMP: 通过突变表型推断
30404558 RGD
involved in response to fluoride IEP
IEP: 通过表达模式推断
24296261 RGD
involved in response to iron(II) ion IEP
IEP: 通过表达模式推断
23187302 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
25040536 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
28231469 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
18059433 RGD
is active in synapse IDA
IDA: 通过直接分析推断
28231469 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

autophagy protein 5

ATG5 autophagy related 5 homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atg5 NCBI NCBI:9474