2. Gene
  3. IL20 - interleukin 20 Gene

IL20 - interleukin 20 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：白细胞介素 20

种属: Homo sapiens

同用名: IL-20; IL10D; ZCYTO10

基因 ID: 50604 | 基因类型: protein coding

关于 IL20

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:206,863,565-206,869,223 (from NCBI)

This gene has 3 transcripts (splice variants), 166 orthologues and 4 paralogues. Low expression observed in reference dataset.

功能概要

该基因编码的蛋白质是一种在结构上与白细胞介素 10 (IL10) 相关的细胞因子。这种细胞因子已被证明可以通过角质形成细胞中的信号转导和转录激活因子 3 (STAT3) 转导其信号。发现这种细胞因子的特异性受体在皮肤中表达，并在牛皮癣皮肤中显着上调，表明这种蛋白质在表皮功能和牛皮癣中的作用。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]

IL20 基因产物(4)

mRNA Protein Name
NM_001385165.1 NP_001372094.1 interleukin-20 isoform 2 precursor
NM_001385166.1 NP_001372095.1 interleukin-20 isoform 1 precursor
NM_001385167.1 NP_001372096.1 interleukin-20 isoform 1 precursor
NM_018724.4 NP_061194.2 interleukin-20 isoform 1 precursor

IL20 蛋白结构

IL10

IL10: Interleukin 10 (36 - 173)

  • 0
  • 100
  • 176 a.a.
蛋白主名 其他名称

interleukin-20

cytokine Zcyto10

重组 IL20 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7214 IL-20 Protein, Human Q9NYY1 (L25-E176) ≥95%
HY-P700111AF Animal-Free IL-20 Protein, Human (His) Q9NYY1 (L25-E176) ≥95%

关联疾病

疾病名称 别名
Psoriasis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99198 Fletikumab Inhibitor 99.24% Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-106647 Abacavir hydroxyacetate Inhibitor 98.29% 否
HY-RS06731 IL20 Human Pre-designed siRNA Set A / 否
HY-RS06732 IL20RA Human Pre-designed siRNA Set A / 否
HY-RS06733 IL20RB Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta IL20 VGNC VGNC:99980
Felis catus IL20 VGNC VGNC:107883
Rattus norvegicus IL20 RGD RGD:1583578
Canis familiaris IL20 VGNC VGNC:41964
Bos taurus IL20 VGNC VGNC:30138
Mus musculus IL20 MGD MGI:1890473
Others IL20 NCBI
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