2. Gene
  3. Tnk2 - tyrosine kinase, non-receptor, 2 Gene

Tnk2 - tyrosine kinase, non-receptor, 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ack; Ack1; Pyk1; Ack-1; Cdgip

基因 ID: 51789 | 基因类型: protein coding

关于 Tnk2

功能概要

Enables WW domain binding activity. Involved in spermatid development. Located in several cellular components, including endosome; growth cone; and neuronal cell body. Is expressed in several structures, including alimentary system; liver; nervous system; retina; and vibrissa. Orthologous to human TNK2 (tyrosine kinase non receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tnk2 基因产物(4)

mRNA Protein Name
NM_001110147.1 NP_001103617.1 activated CDC42 kinase 1 isoform 2
NM_001289443.1 NP_001276372.1 activated CDC42 kinase 1 isoform 3
NM_001347185.1 NP_001334114.1 activated CDC42 kinase 1 isoform 4
NM_016788.3 NP_058068.2 activated CDC42 kinase 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables WW domain binding IPI
IPI: 通过物理相互作用推断
20086093 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16052498 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in spermatid development IGI
IGI: 通过遗传相互作用推断
23562806 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
16052498 MGI
located in dendrite IDA
IDA: 通过直接分析推断
16052498 MGI
located in endosome IDA
IDA: 通过直接分析推断
17182860 MGI
located in growth cone IDA
IDA: 通过直接分析推断
16052498 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
16052498 MGI
located in nucleus IDA
IDA: 通过直接分析推断
20333297 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
20333297 MGI
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
16052498 MGI
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
16052498 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

activated CDC42 kinase 1

Cdc42 GTPase-inhibiting protein

P21cdc42Hs kinase

non-receptor protein tyrosine kinase ACK

tyrosine kinase non-receptor protein 2

Tnk2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Tnk2 O54967 NCK1 Homo sapiens P16333-1
Anti Bait CoIP
16777958
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-12418 Stenoparib Inhibitor ≥98.0% Phase 2
HY-147245 Basroparib Inhibitor 98.49% Phase 1
Pre-clinical Phase
生物活性分子 (37)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15147 XAV-939 Inhibitor 99.91% 否
HY-13990 NVP-TNKS656 99.66% 否
HY-16910 WIKI4 Inhibitor 99.93% 否
HY-12438 G007-LK Inhibitor 99.24% 否
HY-13968 JW 55 Inhibitor 99.83% 否
HY-12975 AZ6102 Inhibitor 99.65% 否
HY-19351 MN-64 Inhibitor 99.61% 否
HY-148063 DB0614 98.80% 否
HY-U00422 K-756 Inhibitor 99.25% 否
HY-15811 XMD8-87 Inhibitor 99.57% 否
HY-148061 DB1113 99.22% 否
HY-101243 XMD16-5 Inhibitor 98.20% 否
HY-123851 MSC2504877 Inhibitor 99.25% 否
HY-148065 FMF-06-098-1 Inhibitor 98.77% 否
HY-126248 Tankyrase-IN-2 Inhibitor 99.06% 否
HY-121719 TIQ-A Inhibitor 99.85% 否
HY-143338 ART-IN-1 Inhibitor 98.91% 否
HY-147886 PARP1-IN-11 Inhibitor 99.42% 否
HY-156332 TNKS-2-IN-2 Inhibitor 99.47% 否
HY-23338 TNKS-2-IN-1 Inhibitor 95.19% 否
HY-100847 AZ0108 Inhibitor / 否
HY-12601 TNKS 22 Inhibitor / 否
HY-13990G NVP-TNKS656 (GMP) / 否
HY-145111 TNK2-IN-1 Inhibitor / 否
HY-146336 PARP1/2/TNKS1/2-IN-1 / 否
HY-153259 TNKS1/2-IN-2 Inhibitor / 否
HY-172747 TNKS-2-IN-3 Inhibitor / 否
HY-173349 TDI-012804 Inhibitor / 否
HY-RS14838 TNK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14843 TNKS2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14844 Tnks2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14845 TNKS2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-153332 Tankyrase-IN-5 Inhibitor / 否
HY-168925 EXQ-2d Inhibitor / 否
HY-173480 TNKS-IN-3 Inhibitor / 否
HY-RS16928 Tnk2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23371 Tnk2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnk2 NCBI NCBI:10188
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