2. Gene
  3. Reck - reversion-inducing-cysteine-rich protein with kazal motifs Gene

Reck - reversion-inducing-cysteine-rich protein with kazal motifs Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: St15; mRECK

基因 ID: 53614 | 基因类型: protein coding

关于 Reck

功能概要

Enables Wnt-protein binding activity; coreceptor activity involved in canonical Wnt signaling pathway; and endopeptidase inhibitor activity. Involved in several processes, including negative regulation of metalloendopeptidase activity; positive regulation of canonical Wnt signaling pathway; and regulation of establishment of blood-brain barrier. Acts upstream of or within several processes, including blood vessel maturation; embryo implantation; and embryonic forelimb morphogenesis. Located in plasma membrane. Part of Wnt signalosome. Is expressed in diaphragm; genitourinary system; and skeletal musculature. Orthologous to human RECK (reversion inducing cysteine rich protein with kazal motifs). [provided by Alliance of Genome Resources, Apr 2022]

Reck 基因产物(1)

mRNA Protein Name
NM_016678.2 NP_057887.2 reversion-inducing cysteine-rich protein with Kazal motifs precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
30026314 MGI
enables coreceptor activity IDA
IDA: 通过直接分析推断
30026314 MGI
enables endopeptidase inhibitor activity IDA
IDA: 通过直接分析推断
11747814 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
30026314 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blood vessel maturation IGI
IGI: 通过遗传相互作用推断
11747814 MGI
acts upstream of or within blood vessel maturation IMP
IMP: 通过突变表型推断
11747814 MGI
involved in canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
30026314 MGI
acts upstream of or within embryo implantation IDA
IDA: 通过直接分析推断
18556655 MGI
acts upstream of or within embryonic forelimb morphogenesis IMP
IMP: 通过突变表型推断
23213437 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: 通过突变表型推断
11747814 MGI
involved in negative regulation of metalloendopeptidase activity IMP
IMP: 通过突变表型推断
24812324 MGI
involved in positive regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
28803732 MGI
involved in regulation of angiogenesis IMP
IMP: 通过突变表型推断
28803732 MGI
involved in regulation of establishment of blood-brain barrier IMP
IMP: 通过突变表型推断
28803732 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Wnt signalosome IDA
IDA: 通过直接分析推断
30026314 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
28803732 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

reversion-inducing cysteine-rich protein with Kazal motifs

Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK)

membrane-anchored glycoprotein RECK

suppression of tumorigenicity 15

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11809 RECK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-124068 LQB-118 / 否
HY-RS19944 Reck Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26446 Reck Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Reck NCBI NCBI:8434
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