2. Gene
  3. Gata4 - GATA binding protein 4 Gene

Gata4 - GATA binding protein 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 54254 | 基因类型: protein coding

关于 Gata4

功能概要

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; NFAT protein binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell growth involved in cardiac muscle cell development; positive regulation of BMP signaling pathway; and transdifferentiation. Located in nucleus. Used to study myocardial infarction. Biomarker of congenital heart disease and pulmonary hypertension. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Gata4 基因产物(1)

mRNA Protein Name
NM_144730.1 NP_653331.1 transcription factor GATA-4
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
8007990 RGD
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
11994297 RGD
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
10330176 RGD
enables NFAT protein binding IPI
IPI: 通过物理相互作用推断
22198280 RGD
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
11994297 RGD
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
20855530 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
20081228 RGD
enables sequence-specific DNA binding IMP
IMP: 通过突变表型推断
12704188 RGD
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
12606287 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac muscle cell differentiation IEP
IEP: 通过表达模式推断
20486789 RGD
involved in cell growth involved in cardiac muscle cell development IDA
IDA: 通过直接分析推断
20971938 RGD
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
17525155 RGD
involved in negative regulation of autophagy IMP
IMP: 通过突变表型推断
19901028 RGD
involved in positive regulation of BMP signaling pathway IDA
IDA: 通过直接分析推断
12606287 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11994297 RGD
involved in regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11827958 RGD
involved in regulation of cardiac muscle cell contraction IMP
IMP: 通过突变表型推断
21702924 RGD
involved in response to mechanical stimulus IDA
IDA: 通过直接分析推断
21084678 RGD
involved in response to vitamin A IEP
IEP: 通过表达模式推断
23333085 RGD
involved in transdifferentiation IMP
IMP: 通过突变表型推断
23948075 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor GATA-4

DNA-binding protein GATA-GT2

GATA-binding factor 4

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-128326 ZAK-IN-1 Inhibitor 98.43% 否
HY-103484 GATA4-NKX2-5-IN-1 Inhibitor 99.24% 否
HY-RS05292 GATA4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174481 Mouse Gata4 mRNA / 否
HY-174673 Human GATA4 mRNA / 否
HY-RS18176 Gata4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24650 Gata4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gata4 NCBI NCBI:2626
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z