Gsdme - gasdermin E Gene

种属: Mus musculus

同用名: Dfna5; Fin15; Dfna5h; EG14210; 2310037D07Rik; 4932441K13Rik

关于 Gsdme

功能概要

Enables cardiolipin binding activity. Involved in cellular response to virus and necrotic cell death. Acts upstream of or within inner ear receptor cell differentiation. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Orthologous to human GSDME (gasdermin E). [provided by Alliance of Genome Resources, Apr 2022]