2. Gene
  3. TSR1 - TSR1 ribosome maturation factor Gene

TSR1 - TSR1 ribosome maturation factor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：TSR1 核糖体成熟因子

种属: Homo sapiens

基因 ID: 55720 | 基因类型: protein coding

关于 TSR1

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:2,322,396-2,336,457 (from NCBI)

This gene has 5 transcripts (splice variants), 224 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 12.8), esophagus (RPKM 10.6) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计参与三顺反子 rRNA 转录物 (SSU-rRNA、5.8S rRNA、LSU-rRNA) 的核酸内切裂解和三顺反子 rRNA 转录物 (SSU-rRNA、5.8S rRNA、LSU-rRNA) 的 SSU-rRNA 成熟。预测位于核仁中。预计是前核糖体的一部分，小亚基前体。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of preribosome, small subunit precursor. [provided by Alliance of Genome Resources, Apr 2022]

TSR1 基因产物(1)

mRNA Protein Name
NM_018128.5 NP_060598.3 pre-rRNA-processing protein TSR1 homolog
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TSR1 蛋白结构

AARP2CN

AARP2CN: AARP2CN (NUC121) domain (228 - 309)

RIBIOP_C

RIBIOP_C: 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal (487 - 773)

  • 0
  • 200
  • 400
  • 600
  • 804 a.a.
蛋白主名 其他名称

pre-rRNA-processing protein TSR1 homolog

TSR1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TSR1 Q2NL82 RHBDD2 Homo sapiens Q6NTF9-3
Y2H Prey Pooling
32296183
种属内
TSR1 Q2NL82 RHBDD2 Homo sapiens Q6NTF9-3
Validated Y2H
32296183
种属内
TSR1 Q2NL82 RHBDD2 Homo sapiens Q6NTF9-3
Y2H Array
32296183
种属内
TSR1 Q2NL82 CIDEB Homo sapiens Q9UHD4
Y2H Prey Pooling
32296183
种属内
TSR1 Q2NL82 CIDEB Homo sapiens Q9UHD4
Validated Y2H
32296183
种属内
TSR1 Q2NL82 CIDEB Homo sapiens Q9UHD4
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Epithelial Malignant Thymoma

Squamoid Thymoma

Thymoma, Epithelial

Well Differentiated Thymic Carcinoma

Thymoma, Type B3
Dendritic Cell Thymoma

Epithelioid Thymoma

Type B Thymoma
Geleophysic Dysplasia 3

GPHYSD3
Otomycosis

Singapore Ear
Geleophysic Dysplasia 2

GPHYSD2

Geleophysic Dwarfism

Dysplasia, Geleophysic, Type 2

Geleophysic Dysplasia
Geleophysic Dysplasia 1

GPHYSD1

Geleophysic Dwarfism

Geleophysic Dysplasia
Sick Building Syndrome
Geleophysic Dysplasia

Geleophysic Dwarfism

Gphysd
Peters-Plus Syndrome

Krause-Kivlin Syndrome

Peters Plus Syndrome

Peters Anomaly

Irido-Corneo-Trabecular Dysgenesis

PTRPLS

Peters Anomaly With Short-Limb Dwarfism

Peters Anomaly-Short Limb Dwarfism Syndrome

Peters Anomaly With Short Limb Dwarfism

Peters Congenital Glaucoma

Krause-Van Schooneveld-Kivlin Syndrome

Peters' Plus Syndrome

Peters'-Plus Syndrome

Anomaly Peters
Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15184 TSR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18050 Tsr1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24524 Tsr1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TSR1 VGNC VGNC:36447
Rattus norvegicus TSR1 RGD RGD:2322150
Mus musculus TSR1 MGD MGI:2144566
Felis catus TSR1 VGNC VGNC:97669
Macaca mulatta TSR1 VGNC VGNC:79512
Others TSR1 NCBI
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