2. Gene
  3. Grk5 - G protein-coupled receptor kinase 5 Gene

Grk5 - G protein-coupled receptor kinase 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Gprk5

基因 ID: 59075 | 基因类型: protein coding

关于 Grk5

功能概要

Predicted to enable beta-adrenergic receptor kinase activity and protein serine/threonine kinase activity. Involved in negative regulation of G protein-coupled receptor signaling pathway; oligodendrocyte differentiation; and response to alkaloid. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be active in cytoplasm. Biomarker of Parkinson's disease and hypertension. Orthologous to human GRK5 (G protein-coupled receptor kinase 5). [provided by Alliance of Genome Resources, Apr 2022]

Grk5 基因产物(1)

mRNA Protein Name
NM_030829.2 NP_110456.2 G protein-coupled receptor kinase 5
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in desensitization of G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
8626574 RGD
involved in negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
30075183 RGD
involved in oligodendrocyte differentiation IEP
IEP: 通过表达模式推断
24613411 RGD
involved in regulation of G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
8626574 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
25213649 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

G protein-coupled receptor kinase 5

g protein-coupled receptor kinase GRK5

相关产品

Pre-clinical Phase
生物活性分子 (23)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103045 CMPD101 Inhibitor 98.95% 否
HY-142812 GRK6-IN-1 99.61% 否
HY-136561 GRK5-IN-2 Inhibitor 99.92% 否
HY-109562A CCG258208 hydrochloride 98.05% 否
HY-18991 CCG215022 Inhibitor 99.79% 否
HY-143248 KR-39038 Inhibitor 99.48% 否
HY-47573 CCG273441 Inhibitor 98.78% 否
HY-139690 CCG258747 Inhibitor 98.96% 否
HY-149720 GRL018-21 Inhibitor 96.91% 否
HY-108601A (S)-Ro 32-0432 Inhibitor / 否
HY-109562 CCG258208 Inhibitor / 否
HY-108601 (S)-Ro 32-0432 free base Inhibitor / 否
HY-118046 GSK2163632A Inhibitor / 否
HY-119232 GSK466317A Inhibitor / 否
HY-150021 GRK5-IN-3 Inhibitor / 否
HY-150022 GRK5-IN-4 Inhibitor / 否
HY-150039 CCG-271423 Inhibitor / 否
HY-150040 CCG-273463 Inhibitor / 否
HY-RS05816 GRK5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-159996 GRL093-22 Inhibitor / 否
HY-174256 GRL-098-22 Inhibitor / 否
HY-RS17288 Grk5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23743 Grk5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grk5 NCBI NCBI:2869
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