2. Gene
  3. Akap6 - A-kinase anchoring protein 6 Gene

Akap6 - A-kinase anchoring protein 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: mAkap

基因 ID: 64553 | 基因类型: protein coding

关于 Akap6

功能概要

Enables several functions, including enzyme binding activity; protein kinase A regulatory subunit binding activity; and transmembrane transporter binding activity. Involved in several processes, including positive regulation of cellular protein metabolic process; regulation of intracellular signal transduction; and regulation of muscle system process. Located in several cellular components, including T-tubule; intercalated disc; and junctional sarcoplasmic reticulum membrane. Part of protein-containing complex. Colocalizes with nuclear envelope. Human ortholog(s) of this gene implicated in anorexia nervosa and ovary epithelial Cancer. Orthologous to human AKAP6 (A-kinase anchoring protein 6). [provided by Alliance of Genome Resources, Apr 2022]

Akap6 基因产物(1)

mRNA Protein Name
NM_022618.2 NP_072140.2 A-kinase anchor protein 6
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables adenylate cyclase binding IDA
IDA: 通过直接分析推断
19574217 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
15182229 RGD
enables molecular adaptor activity IDA
IDA: 通过直接分析推断
11590243 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15652351 RGD
enables protein kinase A binding IDA
IDA: 通过直接分析推断
10413680 RGD
enables protein kinase A regulatory subunit binding IDA
IDA: 通过直接分析推断
9679148 RGD
enables protein phosphatase 2A binding IDA
IDA: 通过直接分析推断
11590243 RGD
enables protein-membrane adaptor activity IDA
IDA: 通过直接分析推断
10413680 RGD
enables transmembrane transporter binding IDA
IDA: 通过直接分析推断
9679148 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
11590243 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cytokine stimulus IMP
IMP: 通过突变表型推断
16177794 RGD
involved in cellular response to epinephrine stimulus IMP
IMP: 通过突变表型推断
11179196 RGD
involved in negative regulation of adenylate cyclase activity IMP
IMP: 通过突变表型推断
19574217 RGD
involved in positive regulation of cAMP-dependent protein kinase activity IMP
IMP: 通过突变表型推断
11179196 RGD
involved in positive regulation of calcineurin-NFAT signaling cascade IMP
IMP: 通过突变表型推断
16306226 RGD
involved in positive regulation of cell growth IMP
IMP: 通过突变表型推断
16177794 RGD
involved in positive regulation of cell growth involved in cardiac muscle cell development IDA
IDA: 通过直接分析推断
16306226 RGD
involved in positive regulation of cell growth involved in cardiac muscle cell development IMP
IMP: 通过突变表型推断
21550986 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
11179196 RGD
involved in positive regulation of release of sequestered calcium ion into cytosol IMP
IMP: 通过突变表型推断
12709444 RGD
involved in positive regulation of translation IMP
IMP: 通过突变表型推断
16306226 RGD
involved in protein-containing complex localization IMP
IMP: 通过突变表型推断
11179196 RGD
involved in regulation of cAMP/PKA signal transduction IDA
IDA: 通过直接分析推断
12709444 RGD
involved in regulation of cardiac muscle cell contraction IMP
IMP: 通过突变表型推断
11179196 RGD
involved in regulation of relaxation of cardiac muscle IMP
IMP: 通过突变表型推断
11179196 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in T-tubule IDA
IDA: 通过直接分析推断
9679148 RGD
located in caveola IDA
IDA: 通过直接分析推断
20224290 RGD
located in cytoplasm IDA
IDA: 通过直接分析推断
9679148 RGD
located in intercalated disc IDA
IDA: 通过直接分析推断
9679148 RGD
located in junctional sarcoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
12709444 RGD
located in nuclear envelope IDA
IDA: 通过直接分析推断
10413680 RGD
located in nuclear membrane IDA
IDA: 通过直接分析推断
10413680 RGD
located in nucleus IDA
IDA: 通过直接分析推断
9679148 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11296225 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
11296225 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
9679148 RGD
located in sarcoplasmic reticulum IDA
IDA: 通过直接分析推断
7721854 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

A-kinase anchor protein 6

A kinase (PRKA) anchor protein 6

AKAP-6

PRKA6

protein kinase A-anchoring protein 6

Akap6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Akap6 Q9WVC7 Ppp3cb Rattus norvegicus P20651
Anti Bait CoIP
19883655
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00521 AKAP6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22383 Akap6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28907 Akap6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Akap6 NCBI NCBI:9472
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