2. Gene
  3. Ppp3cb - protein phosphatase 3 catalytic subunit beta Gene

Ppp3cb - protein phosphatase 3 catalytic subunit beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Calna2

基因 ID: 24675 | 基因类型: protein coding

关于 Ppp3cb

功能概要

Enables calcium-dependent protein serine/threonine Phosphatase activity and Calmodulin binding activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and response to amphetamine. Located in plasma membrane. Part of protein-containing complex. Is active in synapse. Biomarker of schizophrenia. Human ortholog(s) of this gene implicated in aortic valve stenosis. Orthologous to human PPP3CB (protein Phosphatase 3 catalytic subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp3cb 基因产物(1)

mRNA Protein Name
NM_017042.2 NP_058738.1 serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent protein serine/threonine phosphatase activity IDA
IDA: 通过直接分析推断
12135494 RGD
enables calmodulin binding IDA
IDA: 通过直接分析推断
12135494 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15120593 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
12135494 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in muscle cell cellular homeostasis IEP
IEP: 通过表达模式推断
11997253 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
11978799 RGD
involved in protein dephosphorylation IDA
IDA: 通过直接分析推断
12135494 RGD
involved in regulation of insulin secretion IDA
IDA: 通过直接分析推断
11978799 RGD
involved in response to amphetamine IEP
IEP: 通过表达模式推断
11954050 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
11978799 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
16306226 RGD
is active in synapse IDA
IDA: 通过直接分析推断
1313851 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

CAM-PRP catalytic subunit

CNA beta

CaN Abeta

Calcineurin subunit A beta

protein phosphatase 3, catalytic subunit, beta isozyme

protein phosphatase-2Bb

Ppp3cb 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ppp3cb P20651 Akap6 Rattus norvegicus Q9WVC7
Anti Tag CoIP
19883655
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11024 PPP3CB Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppp3cb NCBI NCBI:5532
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