1. Gene
  2. Fzd4 - frizzled class receptor 4 Gene

Fzd4 - frizzled class receptor 4 Gene

种属: Rattus norvegicus

基因 ID: 64558 | 基因类型: protein coding

关于 Fzd4

功能概要

Enables Wnt-protein binding activity and signaling receptor activity. Involved in Wnt signaling pathway and positive regulation of neuron projection arborization. Predicted to be located in several cellular components, including cell surface; dendrite; and glutamatergic synapse. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in exudative vitreoretinopathy 1. Orthologous to human FZD4 (Frizzled class receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Fzd4 基因产物(1)

mRNA Protein Name
NM_022623.3 NP_072145.1 frizzled-4 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
18302287 RGD
enables signaling receptor activity IGI
IGI: 通过遗传相互作用推断
25424568 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
25424568 RGD
involved in positive regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
25424568 RGD
involved in positive regulation of neuron projection arborization IGI
IGI: 通过遗传相互作用推断
25424568 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

frizzled-4

frizzled family receptor 4

frizzled receptor 4

fz-4

rFz4

重组 Fzd4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74142 Frizzled-4/CD344 Protein, Rat (HEK293, His) Q9QZH0/NP_072145.1 (F38-E181) ≥95%
HY-P74143 Frizzled-4/CD344 Protein, Rat (HEK293, Fc) Q9QZH0/NP_072145.1 (F38-E181) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fzd4 NCBI NCBI:8322