2. Gene
  3. Wnt5a - Wnt family member 5A Gene

Wnt5a - Wnt family member 5A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 64566 | 基因类型: protein coding

关于 Wnt5a

功能概要

Predicted to enable protein domain specific binding activity and signaling receptor binding activity. Involved in several processes, including estrous cycle; positive regulation of neuron projection arborization; and response to testosterone. Acts upstream of or within Wnt signaling pathway, planar cell polarity pathway. Located in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to human WNT5A (Wnt family member 5A). [provided by Alliance of Genome Resources, Apr 2022]

Wnt5a 基因产物(1)

mRNA Protein Name
NM_022631.3 NP_072153.2 protein Wnt-5a precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Wnt signaling pathway, planar cell polarity pathway IDA
IDA: 通过直接分析推断
15537637 RGD
involved in cell differentiation IEP
IEP: 通过表达模式推断
16780995 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
20126574 RGD
involved in lung alveolus development IEP
IEP: 通过表达模式推断
17911382 RGD
involved in modulation of chemical synaptic transmission EXP
EXP: 通过实验结果推断
26311509 RGD
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
26311509 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
16909041 RGD
involved in positive regulation of cell-cell adhesion IMP
IMP: 通过突变表型推断
15327998 RGD
involved in positive regulation of dendrite extension IMP
IMP: 通过突变表型推断
25424568 RGD
involved in positive regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
25424568 RGD
involved in positive regulation of neuron projection arborization IGI
IGI: 通过遗传相互作用推断
25424568 RGD
involved in prostate gland development IEP
IEP: 通过表达模式推断
19389372 RGD
involved in regulation of postsynaptic specialization assembly IDA
IDA: 通过直接分析推断
19332546 RGD
involved in regulation of postsynaptic specialization assembly IEP
IEP: 通过表达模式推断
19332546 RGD
involved in regulation of postsynaptic specialization assembly IMP
IMP: 通过突变表型推断
19332546 RGD
involved in regulation of synaptic signaling by nitric oxide EXP
EXP: 通过实验结果推断
26311509 RGD
involved in regulation of synaptic signaling by nitric oxide IDA
IDA: 通过直接分析推断
26311509 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
16551644 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
17911382 RGD
involved in response to hyperoxia IEP
IEP: 通过表达模式推断
17911382 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
20006014 RGD
involved in response to quercetin IEP
IEP: 通过表达模式推断
28032729 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
17218409 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse EXP
EXP: 通过实验结果推断
26311509 RGD
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
26311509 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
16243537 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
26311509 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
19332546 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
19332546 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein Wnt-5a

Wnt-5a protein

wingless-related MMTV integration site 5A

wingless-type MMTV integration site 5A

wingless-type MMTV integration site family, member 5A

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P1416A Foxy-5 TFA Agonist 99.02% Phase 2
HY-P1416 Foxy-5 Agonist 99.56% Phase 2
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99201 Zilovertamab Inhibitor 98.21% Phase 3
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-123071A Box5 TFA Antagonist 99.24% 否
HY-123071 Box5 Antagonist 99.24% 否
HY-12557 γ-Glutamylvaline 99.73% 否
HY-116553 FzM1 Inhibitor 98.62% 否
HY-RS15837 WNT5A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P5171 MDGCEL Antagonist / 否
HY-RS17616 Wnt5a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24076 Wnt5a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wnt5a NCBI NCBI:7474
Mus musculus Wnt5a NCBI NCBI:22418
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