2. Gene
  3. BAD - Bad BCL2-associated agonist of cell death Gene

BAD - Bad BCL2-associated agonist of cell death Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Bad_v1; Bad_v2

基因 ID: 64639 | 基因类型: protein coding

关于 BAD

功能概要

Enables 14-3-3 protein binding activity; protein kinase B binding activity; and protein Phosphatase 2B binding activity. Involved in several processes, including cellular response to chromate; positive regulation of cell death; and response to steroid hormone. Located in cytosol and mitochondrion. Used to study several diseases, including Parkinsonism; diabetic neuropathy; gastric ulcer; impotence; and middle cerebral artery infarction. Biomarker of several diseases, including acute kidney failure; artery disease (multiple); brain disease (multiple); obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in endometrial cancer; lung non-small cell carcinoma; and pancreatic Cancer. Orthologous to human BAD (BCL2 associated agonist of cell death). [provided by Alliance of Genome Resources, Apr 2022]

BAD 基因产物(1)

mRNA Protein Name
NM_022698.2 NP_073189.1 bcl2-associated agonist of cell death
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 14-3-3 protein binding IDA
IDA: 通过直接分析推断
22757651 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10579309 RGD
enables protein kinase B binding IPI
IPI: 通过物理相互作用推断
15120593 RGD
enables protein phosphatase 2B binding IPI
IPI: 通过物理相互作用推断
15120593 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to chromate IEP
IEP: 通过表达模式推断
21262251 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
9813151 RGD
involved in positive regulation of granulosa cell apoptotic process IDA
IDA: 通过直接分析推断
9389536 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
17967733 RGD
involved in response to benzene IEP
IEP: 通过表达模式推断
18093815 RGD
involved in response to calcium ion IEP
IEP: 通过表达模式推断
17663748 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
17196335 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
17283395 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
15845918 RGD
involved in response to glucose IEP
IEP: 通过表达模式推断
15596134 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
18078455 RGD
involved in response to hydrogen peroxide IEP
IEP: 通过表达模式推断
17978575 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
16005992 RGD
involved in response to oleic acid IEP
IEP: 通过表达模式推断
15627513 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
15625305 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
15941375 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
16011741 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
12099715 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
22513421 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bcl2-associated agonist of cell death

Bcl2-antagonist of cell death

bcl-2 associated death agonist

bcl-2-binding component 6

bcl-xL/Bcl-2-associated death promoter

bcl2 antagonist of cell death

bcl2-associated death promoter

相关产品

Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-14266 Dapivirine 99.80% Phase 3
HY-119368 NPB Inhibitor 98.0% Phase 3
HY-50868 Bafetinib 99.18% Phase 2
Pre-clinical Phase
生物活性分子 (24)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-113427 trans-Vaccenic acid 98.0% 否
HY-18095 CX-6258 Inhibitor 98.06% 否
HY-18095A CX-6258 hydrochloride hydrate Inhibitor 99.23% 否
HY-18095B CX-6258 hydrochloride Inhibitor 99.03% 否
HY-111552 PIM1-IN-1 Inhibitor 99.83% 否
HY-P2468 BAD (103-127) (human) Inhibitor 98.80% 否
HY-P2499A BAD (103-127) (human), FAM-labeled TFA Inhibitor 95.10% 否
HY-P2499 BAD (103-127) (human), FAM-labeled Inhibitor / 否
HY-113427S trans-Vaccenic acid-d13 / 否
HY-120035 DD1 99.40% 否
HY-14266A Dapivirine hydrochloride / 否
HY-14266S Dapivirine-d11 / 否
HY-14266S1 Dapivirine-d4 / 否
HY-145844 EGFR-IN-44 / 否
HY-146395 HBV-IN-23 / 否
HY-147342 β-Benzamide adenine dinucleotide Inhibitor / 否
HY-15901 LGB321 Inhibitor / 否
HY-15901A LGB321 monohydrochloride Inhibitor / 否
HY-168338 CB2 receptor agonist 8 / 否
HY-175700 YCJ-02 / 否
HY-P5324 Bad BH3 (mouse) / 否
HY-RS01341 BAD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17318 Bad Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23773 Bad Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens BAD NCBI NCBI:572
Macaca fascicularis BAD NCBI NCBI:102121921
Mus musculus BAD NCBI NCBI:12015
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