2. Gene
  3. Lamtor1 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Gene

Lamtor1 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p18; Pdro; 2400001E08Rik

基因 ID: 66508 | 基因类型: protein coding

关于 Lamtor1

功能概要

Predicted to enable GTPase binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including lysosome localization; positive regulation of MAPK cascade; and regulation of receptor recycling. Predicted to be located in late endosome membrane and membrane raft. Predicted to be part of Ragulator complex. Predicted to be active in lysosome. Is expressed in several structures, including adipose tissue; alimentary system; early conceptus; nervous system; and reproductive system. Orthologous to human LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and mTOR Activator 1). [provided by Alliance of Genome Resources, Apr 2022]

Lamtor1 基因产物(1)

mRNA Protein Name
NM_025605.3 NP_079881.2 ragulator complex protein LAMTOR1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19177150 MGI
enables protein-membrane adaptor activity IDA
IDA: 通过直接分析推断
30020076 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endosomal transport IMP
IMP: 通过突变表型推断
19177150 MGI
involved in endosome organization IMP
IMP: 通过突变表型推断
19177150 MGI
involved in lysosome localization IMP
IMP: 通过突变表型推断
19177150 MGI
involved in lysosome organization IMP
IMP: 通过突变表型推断
19177150 MGI
involved in positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
19177150 MGI
involved in positive regulation of TORC1 signaling IDA
IDA: 通过直接分析推断
30020076 MGI
involved in protein localization IMP
IMP: 通过突变表型推断
19177150 MGI
involved in protein localization to membrane IDA
IDA: 通过直接分析推断
30020076 MGI
involved in regulation of receptor recycling IMP
IMP: 通过突变表型推断
19177150 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in lysosomal membrane IDA
IDA: 通过直接分析推断
30020076 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ragulator complex protein LAMTOR1

RhoA activator C11orf59 homolog

late endosomal/lysosomal adaptor and MAPK and MTOR activator 1

lipid raft adaptor protein p18

p27Kip1-releasing factor from RhoA

p27RF-Rho

ragulator complex protein PDRO

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-176166 PD-M6 Degrader / 否
HY-RS07513 LAMTOR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20212 Lamtor1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26717 Lamtor1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lamtor1 NCBI NCBI:55004
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