Brpf1 - bromodomain and PHD finger containing, 1 Gene

中文名称：含溴结构域和 PHD 指，1

种属: Rattus norvegicus

关于 Brpf1

功能概要

预测该基因编码的蛋白可启动乙酰转移酶激活剂活性和组蛋白结合活性。预计参与组蛋白H3-K14乙酰化；组蛋白 H3-K23 乙酰化；和转录的正调控，DNA 模板。预测作用于普通骨髓祖细胞增殖的上游或内部；调节成纤维细胞增殖；和管形态发生。预测位于胞质溶胶中；核;和质膜。预计是 MOZ/MORF 组蛋白乙酰转移酶复合物的一部分。与人类 BRPF1 同源（溴结构域和 PHD 指包含 1）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable acetyltransferase activator activity and histone binding activity. Predicted to be involved in histone H3-K14 acetylation; histone H3-K23 acetylation; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within common myeloid progenitor cell proliferation; regulation of fibroblast proliferation; and tube morphogenesis. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be part of MOZ/MORF Histone Acetyltransferase complex. Orthologous to human BRPF1 (bromodomain and PHD finger containing 1). [provided by Alliance of Genome Resources, Apr 2022]