2. Gene
  3. Dapk1 - death associated protein kinase 1 Gene

Dapk1 - death associated protein kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: D13Ucla1; DAP-Kinase

基因 ID: 69635 | 基因类型: protein coding

关于 Dapk1

功能概要

Enables ATP binding activity; Calmodulin binding activity; and protein kinase activity. Involved in several processes, including cellular response to interferon-gamma; protein phosphorylation; and regulation of NMDA Receptor activity. Acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; liver and biliary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in urinary bladder Cancer. Orthologous to human DAPK1 (death associated protein kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Dapk1 基因产物(3)

mRNA Protein Name
NM_001285917.1 NP_001272846.1 death-associated protein kinase 1 isoform 2
NM_029653.3 NP_083929.2 death-associated protein kinase 1 isoform 1
NM_134062.2 NP_598823.1 death-associated protein kinase 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
11485996 MGI
enables calmodulin binding IDA
IDA: 通过直接分析推断
11485996 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20053891 MGI
enables protein kinase activity IDA
IDA: 通过直接分析推断
20053891 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to type II interferon IMP
IMP: 通过突变表型推断
23071094 MGI
acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors IGI
IGI: 通过遗传相互作用推断
20053891 MGI
acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors IMP
IMP: 通过突变表型推断
15010850 MGI
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
11485996 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
11485996 MGI
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
11485996 MGI
involved in regulation of NMDA receptor activity IMP
IMP: 通过突变表型推断
20141836 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15010850 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20141836 MGI
is active in postsynaptic density IDA
IDA: 通过直接分析推断
20141836 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

death-associated protein kinase 1

DAP kinase 1

Dapk1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Dapk1 Q80YE7 Grin2b Mus musculus Q01097
Anti Bait CoIP
20141836
种属内
Dapk1 Q80YE7 Grin2b Mus musculus Q01097
IF
20141836
种属内
Dapk1 Q80YE7 Grin2b Mus musculus Q01097
Pull Down
20141836
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-123581 Quinocetone Activator 98.00% 否
HY-175477 UNC9750 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dapk1 NCBI NCBI:1612
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z