2. Gene
  3. Sulf2 - sulfatase 2 Gene

Sulf2 - sulfatase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MSulf-2; mKIAA1247; 2010004N24Rik

基因 ID: 72043 | 基因类型: protein coding

关于 Sulf2

功能概要

Enables N-acetylglucosamine-6-sulfatase activity. Involved in several processes, including esophagus smooth muscle contraction; glomerular filtration; and skeletal system development. Acts upstream of or within several processes, including liver regeneration; positive regulation of canonical Wnt signaling pathway; and regulation of hepatocyte proliferation. Located in plasma membrane. Is expressed in several structures, including embryo mesenchyme; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human SULF2 (sulfatase 2). [provided by Alliance of Genome Resources, Apr 2022]

Sulf2 基因产物(4)

mRNA Protein Name
NM_001252578.1 NP_001239507.1 extracellular sulfatase Sulf-2 isoform 1 precursor
NM_001252579.1 NP_001239508.1 extracellular sulfatase Sulf-2 isoform 2
NM_001355619.1 NP_001342548.1 extracellular sulfatase Sulf-2 isoform 1 precursor
NM_028072.5 NP_082348.2 extracellular sulfatase Sulf-2 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables N-acetylglucosamine-6-sulfatase activity IMP
IMP: 通过突变表型推断
18687675 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bone development IGI
IGI: 通过遗传相互作用推断
17593974 MGI
involved in cartilage development IMP
IMP: 通过突变表型推断
20479257 MGI
involved in chondrocyte development IMP
IMP: 通过突变表型推断
20479257 MGI
involved in embryonic skeletal system development IGI
IGI: 通过遗传相互作用推断
18213582 MGI
involved in esophagus smooth muscle contraction IGI
IGI: 通过遗传相互作用推断
17720696 MGI
involved in glial cell-derived neurotrophic factor receptor signaling pathway IDA
IDA: 通过直接分析推断
17720696 MGI
involved in glomerular basement membrane development IGI
IGI: 通过遗传相互作用推断
21719793 MGI
involved in glomerular filtration IGI
IGI: 通过遗传相互作用推断
21719793 MGI
involved in heparan sulfate proteoglycan metabolic process IMP
IMP: 通过突变表型推断
18687675 MGI
involved in innervation IGI
IGI: 通过遗传相互作用推断
17720696 MGI
involved in kidney development IGI
IGI: 通过遗传相互作用推断
17593974 MGI
acts upstream of or within liver regeneration IMP
IMP: 通过突变表型推断
23740243 MGI
involved in negative regulation of fibroblast growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
17593974 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
23740243 MGI
involved in positive regulation of vascular endothelial growth factor production IGI
IGI: 通过遗传相互作用推断
21719793 MGI
acts upstream of or within regulation of hepatocyte proliferation IMP
IMP: 通过突变表型推断
23740243 MGI
acts upstream of or within response to wounding IMP
IMP: 通过突变表型推断
23740243 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
21719793 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

extracellular sulfatase Sulf-2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14012 SULF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20108 Sulf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26612 Sulf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sulf2 NCBI NCBI:55959
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