2. Gene
  3. Rspo3 - R-spondin 3 Gene

Rspo3 - R-spondin 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Thsd2; Cristin1; 2810459H04Rik

基因 ID: 72780 | 基因类型: protein coding

关于 Rspo3

功能概要

Enables Frizzled binding activity and heparin binding activity. Involved in blood vessel remodeling; positive regulation of non-canonical Wnt signaling pathway; and sprouting angiogenesis. Acts upstream of or within angiogenesis; branching involved in labyrinthine layer morphogenesis; and positive regulation of canonical Wnt signaling pathway. Located in extracellular region. Is expressed in several structures, including central nervous system; genitourinary system; heart; limb; and skeleton. Orthologous to human RSPO3 (R-spondin 3). [provided by Alliance of Genome Resources, Apr 2022]

Rspo3 基因产物(1)

mRNA Protein Name
NM_028351.3 NP_082627.3 R-spondin-3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables frizzled binding IPI
IPI: 通过物理相互作用推断
16543246 MGI
enables heparin binding IDA
IDA: 通过直接分析推断
16543246 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
16543246 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
18842812 MGI
involved in blood vessel remodeling IMP
IMP: 通过突变表型推断
26766444 MGI
acts upstream of or within branching involved in labyrinthine layer morphogenesis IMP
IMP: 通过突变表型推断
16963017 MGI
acts upstream of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
18842812 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
16543246 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
18842812 MGI
involved in positive regulation of non-canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
26766444 MGI
involved in sprouting angiogenesis IMP
IMP: 通过突变表型推断
26766444 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
16543246 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

R-spondin-3

R-spondin 3 homolog

cabriolet

cristin 1

cysteine-rich and single thrombospondin domain-containing protein 1

nucleopondin

roof plate-specific spondin-3

thrombospondin, type I, domain 2

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99401 Rosmantuzumab Inhibitor 99.29% Phase 1
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12307 RSPO3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17424 Rspo3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23879 Rspo3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rspo3 NCBI NCBI:84870
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